Sarcoma Clinical Trials

A listing of Sarcoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 90 clinical trials
PLX3397 Plus Sirolimus in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors

The purpose of this study is to determine if treatment with PLX3397 and Sirolimus will be tolerated and result in shrinking of the cancer or stopping the cancer from growing. In the phase I portion, the maximum tolerate dose of the study drug will be determined. In the Phase II …

neutrophil count
mpnst
small molecule
metastasis
KIT
  • 0 views
  • 09 Sep, 2021
  • 5 locations
Perioperative Use of Tranexamic (TXA) in Bone Tumor Surgery Reduce Blood Loss and Transfusion Requirements.

The purpose of this trial is to investigate whether previously reported benefit of Tranexamic acid in pediatric orthopedic surgeries could be recapitulated in bone tumor surgeries or not through a double blinded randomized controlled trial done in children cancer hospital 57357.

cancer chemotherapy
cancer
  • 0 views
  • 04 Sep, 2021
  • 1 location
Nivolumab or Nivolumab and Azacitidine in Patients With Recurrent Resectable Osteosarcoma

The purpose of this study is to evaluate the safety and efficacy of nivolumab, or nivolumab in combination with azacitidine in participants with recurrent, resectable osteosarcoma

resectable osteosarcoma
azacitidine
metastatic disease
metastasis
cancer chemotherapy
  • 31 views
  • 17 Sep, 2021
  • 24 locations
Exercise Intervention for Bone Tumor Patients

The proGait-study is a two-arm exercise intervention study for AYA-patients with lower extremity tumor endoprosthesis in the follow-up care. This clinical trial will investigate the effects of an 8-week personalized multi-modal exercise intervention of lower extremity muscles on gait quality in adolescents and young adults with cancer diagnosis beginning at …

cancer
  • 0 views
  • 06 Sep, 2021
  • 1 location
PLX3397 in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN)

Background Some people with cancer have solid tumors. Others have refractory leukemia. This doesn t go away after treatment. Researchers want to see if a drug called PLX3397 can shrink tumors or stop them from growing. Objectives To find the highest safe dose and side effects of PLX3397. To see …

neutrophil count
mpnst
corticosteroids
measurable disease
hydroxyurea
  • 48 views
  • 12 Sep, 2021
  • 1 location
Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Soft Tissue or Bone Sarcoma Metastatic to the Lungs

This phase I/II trial studies the side effects of pulmonary suffusion in controlling minimal residual disease in patients with soft tissue or bone sarcoma that has spread to the lungs. Pulmonary

metastasectomy
sarcoma
measurable disease
isolated chemotherapeutic lung perfusion
antineoplastic
  • 0 views
  • 04 Sep, 2021
  • 1 location
Phase 2 CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients With Sarcoma

The objective of this study is to assess safety and efficacy of CAB-AXL-ADC in solid tumors

renal function
measurable disease
solid tumor
kidney function test
cab-axl-adc
  • 55 views
  • 18 Sep, 2021
  • 15 locations
Treatment of Milademetan Versus Trabectedin in Patient With Dedifferentiated Liposarcoma

Randomized, multicenter, open-label, Phase 3 registration study designed to evaluate the safety and efficacy of milademetan compared to trabectedin in patients with unresectable (i.e., where resection is deemed to cause unacceptable morbidity or mortality) or metastatic DD liposarcoma that progressed on 1 or more prior systemic therapies, including at least …

neutrophil count
trabectedin
platelet count
liposarcoma
cancer chemotherapy
  • 0 views
  • 04 Sep, 2021
  • 1 location
ENVASARC: Envafolimab And Envafolimab With Ipilimumab In Patients With Undifferentiated Pleomorphic Sarcoma Or Myxofibrosarcoma

patients with locally advanced, unresectable or metastatic undifferentiated pleomorphic sarcoma (UPS)/myxofibrosarcoma (MFS) who have progressed on one or two lines of chemotherapy.

  • 0 views
  • 17 Sep, 2021
  • 25 locations
Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their Caregivers

Background People cope with cancer in different ways. Mindfulness means focusing on the present moment with an open mind. Researchers want to see if this can help children and young adults with a high-grade high-risk cancer with poor prognosis. Objective To learn if mindfulness is feasible and acceptable for children …

KIT
myeloid leukemia
lymphoid leukemia
cancer
brain tumor
  • 14 views
  • 12 Sep, 2021
  • 1 location