Sarcoma Clinical Trials

A listing of Sarcoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 84 clinical trials
Testing the Addition of Nivolumab to Chemotherapy in Treatment of Soft Tissue Sarcoma

This phase II trial studies how well paclitaxel with and without nivolumab works in treating patients with soft tissue sarcoma that have not received taxane drugs, and how well nivolumab and

  • 0 views
  • 23 Sep, 2021
  • 93 locations
Pomalidomide in Combination With Liposomal Doxorubicin in People With Advanced or Refractory Kaposi Sarcoma

Background Kaposi sarcoma (KS) is a cancer most often seen in people with HIV. It causes lesions. These are usually on the skin but sometimes in the lymph nodes

neutrophil count
cancer
antiretroviral therapy
protease
measurable disease
  • 11 views
  • 12 Sep, 2021
  • 1 location
NHS-IL12 Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma

Background Kaposi sarcoma (KS) tumors grow on the skin, lymph nodes, lungs, bone, and gastrointestinal tract. KS often affects people with immune deficiencies

cancer chemotherapy
direct bilirubin
systemic therapy
monoclonal antibodies
atazanavir
  • 12 views
  • 12 Sep, 2021
  • 1 location
Study of Liposomal Annamycin for the Treatment of Subjects With Soft-Tissue Sarcomas (STS) With Pulmonary Metastases

This is a multi-center, open-label, single-arm study that in Phase 1b will determine the maximum tolerated dose (MTD)/ recommended phase 2 dose (RP2D) and safety of L-Annamycin and in Phase 2 will explore the efficacy of L- Annamycin as a single agent for the treatment of subjects with STS with …

cancer chemotherapy
  • 0 views
  • 20 Sep, 2021
  • 2 locations
Lymphodepletion Plus Adoptive Cell Therapy With High Dose IL-2 in Adolescent and Young Adult Patients With Soft Tissue Sarcoma

This is a single-arm trial that will evaluate the safety and feasibility of the Tumor-infiltrating lymphocyte (TIL) treatment and the persistence of TIL survival in vivo following treatment

cancer chemotherapy
soft tissue sarcoma
metastasis
measurable disease
  • 0 views
  • 24 Sep, 2021
  • 1 location
Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi Sarcoma

Background Kaposi Sarcoma (KS) is common in people with human immunodeficiency virus (HIV) but can also occur in people who do not have HIV. KS tumors usually

systemic therapy
atazanavir
neutrophil count
AIDS
cancer
  • 0 views
  • 22 Sep, 2021
  • 1 location
Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma

, rhabdomyosarcoma and other soft tissue sarcoma and to measure the length of time during and after treatment that their disease does not get worse. Researchers also want to find out if nab-paclitaxel combined with

metastasis
nervous
graft versus host disease
cancer
myelosuppressive chemotherapy
  • 146 views
  • 12 Sep, 2021
  • 16 locations
Trastuzumab Deruxtecan for the Treatment of HER2+ Newly Diagnosed or Recurrent Osteosarcoma

This phase II trial studies the effects of trastuzumab deruxtecan in treating patients with HER2 positive osteosarcoma that is newly diagnosed or has come back (recurrent). Trastuzumab deruxtecan is a monoclonal antibody, called trastuzumab, linked to a chemotherapy drug called deruxtecan. Trastuzumab attaches to HER2 positive cancer cells in a …

graft versus host disease
neutrophil count
cancer
myelosuppressive chemotherapy
pegfilgrastim
  • 2 views
  • 22 Sep, 2021
  • 15 locations
A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg

The purpose of this study is to find out whether giving the study drug pembrolizumab in combination with the chemotherapy drugs melphalan and dactinomycin, delivered directly to the affected arm or leg using a technique called isolated limb infusion (ILI), is a safe treatment that can delay the time before …

cancer chemotherapy
metastasis
undifferentiated pleomorphic sarcoma
systemic therapy
neutrophil count
  • 0 views
  • 16 Sep, 2021
  • 7 locations
Palliative Lattice Stereotactic Body Radiotherapy (SBRT) for Patients With Sarcoma Thoracic Abdominal and Pelvic Cancers

This is a study evaluating the safety and efficacy of Lattice SBRT for patients with large tumors ( 4.5 cm) planning to undergo palliative radiotherapy.

cancer
  • 0 views
  • 24 Sep, 2021
  • 1 location