Sarcoma Clinical Trials

A listing of Sarcoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 73 clinical trials
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CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Synovial Sarcoma

This study is being conducted to test the safety and efficacy of ramucirumab in combination with other chemotherapy in the treatment of relapsed, recurrent, or refractory synovial sarcoma (SS

  • 7 views
  • 25 Oct, 2021
  • 70 locations
None
Investigating Safety Tolerability Efficacy and PK of Olaparib in Paediatric Patients With Solid Tumours

A study to find out whether olaparib is safe and well tolerated when administered to children and adolescents with solid tumours

  • 16 views
  • 27 Oct, 2021
  • 20 locations
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Trastuzumab Deruxtecan in Participants With HER2-overexpressing Advanced or Metastatic Colorectal Cancer

This study will evaluate the efficacy, safety, and pharmacokinetics of Trastuzumab deruxtecan (T-DXd) in participants with human epidermal growth factor 2 (HER2)-overexpressing locally advanced, unresectable, or metastatic colorectal cancer (mCRC).

  • 0 views
  • 20 Oct, 2021
  • 77 locations
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A Study of ERAS-007 in Patients With Advanced Gastrointestinal Malignancies

To evaluate the safety and tolerability of escalating doses of ERAS-007 in combination with other cancer therapies in study participants with advanced GI malignancies. To determine the Maximum Tolerated Dose (MTD) and/or Recommended Dose (RD) of ERAS-007 administered in combination with other cancer therapies. To evaluate the antitumor activity of …

  • 0 views
  • 14 Oct, 2021
  • 1 location
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A Study to Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children Adolescents and Young Adults With Relapsed and Refractory Osteosarcoma

This Is a Multicenter, Randomized, Open-Label, Parallel-Group, Phase 2 Study to Compare the Efficacy and Safety of Lenvatinib in Combination with Ifosfamide and Etoposide Versus Ifosfamide and Etoposide in Children, Adolescents, and Young Adults with Relapsed or Refractory Osteosarcoma.

refractory osteosarcoma
nitrosoureas
ototoxicity
cancer chemotherapy
cancer
  • 50 views
  • 27 Oct, 2021
  • 81 locations
None
CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Desmoplastic Small Round Cell Tumor

This study is being conducted to test the safety and efficacy of ramucirumab in combination with other chemotherapy in the treatment of relapsed, recurrent, or refractory desmoplastic small round cell tumor (DSRCT) in children and young adults. This trial is part of the CAMPFIRE master protocol which is a platform …

vinorelbine
immunomodulators
measurable disease
desmoplastic
cancer chemotherapy
  • 4 views
  • 26 Oct, 2021
  • 73 locations
None
Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 Mutations

This is an open-label, multicenter Phase 1 study to evaluate safety, tolerability and preliminary efficacy of oral LY3410738 in patients with IDH1 R132-mutant advanced solid tumor types, including but not limited to cholangiocarcinoma, chondrosarcoma, and glioma.

immunomodulators
cancer chemotherapy
gemcitabine
measurable disease
drainage
  • 1 views
  • 21 Oct, 2021
  • 51 locations
None
Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)

To evaluate the safety and tolerability of sotorasib administered in investigational regimens in adult participants with KRAS p.G12C mutant advanced solid tumors.

  • 26 views
  • 27 Oct, 2021
  • 92 locations
None
A Study to Evaluate Tabelecleucel in Participants With Epstein-barr Virus-associated Diseases

The purpose of this study is to assess the efficacy and safety of tabelecleucel in participants with Epstein-Barr virus (EBV) associated diseases.

chemotherapy regimen
measurable disease
bone marrow procedure
systemic disease
fever
  • 0 views
  • 20 Oct, 2021
  • 23 locations
None
Enhancing Self Care Among Oral Cancer Survivors: The Empowered Survival Trial

Project's goal is evaluate an online tool the research team created called Empowered Survivor (ES) against a free online self-management intervention developed for cancer survivors by the

carcinoma of oropharynx
oropharyngeal
oral cancer
  • 0 views
  • 25 Oct, 2021
  • 1 location