Rheumatoid Arthritis Clinical Trials

A listing of Rheumatoid Arthritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 52 clinical trials
Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC).

Background Bile duct cancer is cancer of the slender tubes of the biliary tract. These tubes carry bile through the liver. Such cancer tumors often have an abnormal or mutated gene. Researchers think a mix of drugs can slow the progression of gene-mutated cancers of the biliary tract. Objective To …

KRAS
EGFR
measurable disease
cancer
hydroxychloroquine
  • 0 views
  • 24 Sep, 2021
  • 1 location
Study of Baricitinib a JAK1/2 Inhibitor in Chronic Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation

Background Chronic graft versus host disease (cGVHD) can affect people who had a hematopoietic stem cell transplant using donor cells. It is often fatal. It is usually treated with high doses of steroids. But that helps only about half the people in the long term. Researchers want to see if …

neutrophil count
urine test
cell transplantation
prednisone
systemic therapy
  • 23 views
  • 24 Sep, 2021
  • 1 location
Validation of Sleep Questionnaires in the Down Syndrome Population

This will be a prospective validation study of a sample of consecutive pediatric Down syndrome patients who are seen through the weekly Down syndrome clinic at OHSU/Doernbecher's. Questionnaires will be administered to approximately 5 new patients per month. Since this population has a higher prevalence of OSA than the general …

polysomnography
  • 0 views
  • 22 Sep, 2021
  • 1 location
Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma Cholangiocarcinoma and Other Mesothelin Expressing Solid Tumors

Background The protein mesothelin is found on many kinds of tumors. The drug LMB-100 targets cancer cells that make this protein. Researchers want to see if LMB-100 combined with another drug can help people with these tumors. Objective To find a safe dose of LMB-100 plus tofacitinib in people with …

  • 2 views
  • 22 Sep, 2021
  • 1 location
Prospective Observational Study of Filgotinib in Subjects With Rheumatoid Arthritis

An observational study to describe the effectiveness, safety, and patient-reported outcomes in patients with moderate to severe active rheumatoid arthritis (RA) receiving filgotinib in real

  • 0 views
  • 18 Sep, 2021
  • 22 locations
Smart Marker Annunciating Response to Rheumatologic Treatments SMART T

European recommendations indicate to start a conventional synthetic disease modifying antirheumatic drug (csDMARD) as soon as possible to reach the remission in early RA or low disease activity

antirheumatics
DMARD
methotrexate
remission
  • 0 views
  • 17 Sep, 2021
  • 15 locations
Study to Gather Information on the Safety and How Radium-223 Dichloride an Alpha Particle-emitting Radioactive Agent Works Under Routine Clinical Practice in Taiwan in Patients With Castration-resistant Prostate Cancer (CRPC) Which Has Spread to the Bone

bone and were treated with radium-223 in routine clinical practice in Taiwan. Radium-223 (Ra-223) is an alpha particle-emitting radioactive agent approved for the treatment of men with metastatic

metastasis
bone metastases
metastatic castration-resistant prostate cancer
adenocarcinoma
  • 0 views
  • 24 Sep, 2021
  • 1 location
Peri-operative Dynamics of the Growth Hormone Axis in Subjects With Acromegaly

Acromegaly is a rare disorder characterized by excessive production of growth hormone most often by a pituitary adenoma. A pituitary adenoma is a tumor, almost always benign or non-cancerous, that grows on the pituitary, a small gland located at the base of the brain. Treatment of acromegaly usually involves surgery, …

oral glucose tolerance test
adenoma
insulin-like growth factor
pituitary
tolerance test
  • 73 views
  • 22 Sep, 2021
  • 1 location
Study To Assess Frequency Of Serious Infections In Clinical Practice In Japan For Adult Participants With Rheumatoid Arthritis Receiving Oral RINVOQ Tablets

Rheumatoid Arthritis (RA) is a chronic inflammatory disease causing pain, stiffness, swelling and loss of joint function. RA can reduce the ability to perform everyday tasks. The purpose of this

stiffness
  • 0 views
  • 22 Sep, 2021
  • 24 locations
A Study of Oral Upadacitinib Tablets to Assess Treatment Patterns Achievement of Treatment Targets and Maintenance of Response in Adult Participants With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function. Despite the range of treatment options for RA steadily increasing

glucocorticoids
prednisone
remission
stiffness
  • 7 views
  • 22 Sep, 2021
  • 234 locations