Psoriasis and Psoriatic Disorders Clinical Trials

A listing of Psoriasis and Psoriatic Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 115 clinical trials
Dose Reduction of IL17 and IL23 Inhibitors in Psoriasis

The main objective of this study is to investigate whether controlled dose reduction of IL17 or IL23 inhibiting biologics is not inferior compared to usual care in psoriasis patients. Therefore, a pragmatic, multicentre, randomized, controlled, non-inferiority study will be carried out.

plaque psoriasis
risankizumab
secukinumab
ixekizumab
brodalumab
  • 0 views
  • 28 Nov, 2021
  • 2 locations
Immunogenetic Profiling of Goeckerman Therapy in the Treatment of Psoriasis Vulgaris

This study examines the effect of Goeckerman therapy (a combination of phototherapy and topical crude coal tar), crude coal tar alone, and phototherapy alone on the immunologic and genetic environment within psoriatic skin lesions.

topical agents
skin lesion
plaque psoriasis
psoriasis vulgaris
phototherapy
  • 22 views
  • 11 Apr, 2022
  • 1 location
Metabolic Biomarkers in Hashimoto's Thyroiditis and Psoriasis

Hashimoto's disease (HT) and psoriasis (PsO) have a significant impact on patient's quality of everyday life, and early diagnosis is critical for the symptoms management and prognosis. There is evidence that HT and PsO share common metabolic pathways that relate to their pathogenesis, and are affected by dietary and lifestyle …

  • 69 views
  • 23 Feb, 2021
  • 1 location
An Open-label, Long Term Safety Trial of Spesolimab Treatment in Patients With Palmoplantar Pustulosis (PPP) Who Have Completed Previous BI Spesolimab Trials

This study is open to people with palmoplantar pustulosis who took part in previous clinical studies of a medicine called spesolimab. Participants who benefited from spesolimab treatment in the previous studies can join this study. The purpose of this study is to find out how safe spesolimab is and whether …

palmoplantar pustulosis
  • 19 views
  • 20 Sep, 2022
  • 9 locations
The Anti-inflammatory Effects of Harkány Medicinal Water

The study aims to provide evidence on the effectiveness of Harkny medicinal water in psoriatic and rheumatoid arthritis patients using subjective and objective methods. It is a cross-over study, so first half of patients will receive medicinal water, the other half will receive tap water treatment, and after 6 months …

psoriasis vulgaris
skin lesion
arthritis
  • 0 views
  • 27 Feb, 2022
  • 3 locations
Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

Background Psoriasis causes chronic inflammation in the body. Researchers want to see if a kind of vitamin B3 dietary supplement can help. This might lead to more treatment options. Objective To test if the dietary supplement nicotinamide riboside can improve immune system function in the blood and skin of people …

niacin
vitamins
body mass index
Accepts healthy volunteers
  • 83 views
  • 16 Sep, 2022
  • 1 location
Psoriatic Arthritis and Psoriasis Treatment Decision Aid (DA)

The purpose of this study is to create and test a patient decision aid that facilitates the shared decision-making process when patients with psoriasis and/or psoriatic arthritis are starting or switching to a new therapy.

psoriasis treatment
psoriasis
biosimilar
DMARD
arthritis
  • 0 views
  • 24 Mar, 2022
  • 1 location
Severe Psoriatic Arthritis - Early intervEntion to Control Disease: the SPEED Trial (SPEED)

SPEED is a three arm interventional trial nested within a cohort (Trials Within Cohorts or TWiCs design). This tests more aggressive early therapy in patients newly diagnosed with moderate to severe PsA. Arm 1 will receive standard step up therapy in the cohort and act as the control group. Arm …

anti-rheumatic drugs
adalimumab
tumour necrosis
arthritis
methotrexate
  • 2 views
  • 02 Jun, 2022
  • 1 location
Diet Interventions in Psoriatic Arthritis (DIPSA)

The purpose of this study is to learn whether changing diet impacts psoriatic arthritis (PsA).

anti-rheumatic drugs
DMARD
body mass index
arthritis
  • 0 views
  • 23 Mar, 2022
  • 2 locations
Molecular Effects of Apremilast in the Synovium of Psoriatic Arthritis Patients

This study assess the genomics profiles in synovial biopsies obtained prior to, and 24 weeks after an immunomodulator agent (Apremilast) in patients with active psoriatic arthritis who are naive to treatment with a conventional synthetic DMARDs (such as methotrexate).

  • 2 views
  • 27 Jan, 2021
  • 1 location