Psoriasis and Psoriatic Disorders Clinical Trials

A listing of Psoriasis and Psoriatic Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 115 clinical trials
Psoriatic Arthritis D2P Screening

The overarching goal of this study is to develop a direct-to-patient screening approach that will improve early Psoriatic Arthritis (PsA) detection in patients with psoriasis. Previously developed screening questionnaires were intended for use in the setting of a doctor's office to assist providers with referral decisions. However, these screening questionnaires …

arthritis
psa screening
psoriasis
  • 53 views
  • 22 Mar, 2022
  • 2 locations
Comparative Study of BAT2506 With Simponi in Participants With Active Psoriatic Arthritis

This is a multicenter, double-blind, randomized, parallel-group study to compare the efficacy,pharmacodynamics (PD), pharmacokinetics (PK), safety, and immunogenicity of BAT2506 versus Simponi in participants with active PsA. The study will consist of up to 4-week Screening Period, a 52-week Treatment Period, and a 8-week Safety Follow-up Period.

joints tender
arthritis
rheumatoid factor
DMARD
NSAID
  • 0 views
  • 24 Sep, 2021
  • 1 location
Effects of Treatment With Biological Agents on Vascular and Cardiac Function in Psoriasis

Psoriasis has been associated with an increasing risk for atherosclerosis. The investigators investigated whether surrogate markers of subclinical atherosclerosis, vascular dysfunction and myocardial dysfunction are impaired in patients with psoriasis compared to normal controls ,coronary artery disease patients and untreated hypertension subjects. The investigators also examined the effect of treatment …

cyclosporine
atherosclerosis
apremilast
Accepts healthy volunteers
secukinumab
  • 0 views
  • 18 Apr, 2022
  • 1 location
Assessing Patient Confidence in Biologic Medications

In dermatology, biologic medications are used to treat conditions such as moderate-to-severe psoriasis. These medications generally function to decrease inflammation or disrupt the inflammatory cycle. Examples of biologic medications commonly used in dermatology include tumor necrosis factor-alpha (TNF-alpha), blockers/inhibitors (etanercept, infliximab, certolizumab pegol, golimumab), interleukin 12/23 blockers (ustekinumab) and interleukin …

infliximab
tumor necrosis factor
secukinumab
etanercept
certolizumab pegol
  • 67 views
  • 25 Apr, 2022
  • 1 location
A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With Plaque Psoriasis

This study is to evaluate the safety, the systemic exposure of halobetasol propionate (HP), and the hypothalamic-pituitary-adrenal (HPA) axis suppression potential for topically applied IDP-122 lotion in pediatric participants with moderate to severe plaque psoriasis.

pituitary
topical agents
plaque psoriasis
  • 4 views
  • 19 Jun, 2022
  • 6 locations
Rimegepant in Moderate Plaque-type Psoriasis

The purpose of this study is to examine the use of a new investigational medication for the treatment of moderate plaque-type psoriasis. The study medication is rimegepant, an orally administered small molecule competitive inhibitor of the calcitonin gene-related peptide (CGRP) receptor. This medication, rimegepant, has been approved by the FDA …

  • 0 views
  • 19 Nov, 2021
  • 1 location
A Safety and Pharmacokinetics Study of IDP-118 Lotion in Pediatric Participants With Plaque Psoriasis

This study is to evaluate the safety, the systemic exposure, and the hypothalamic-pituitary-adrenal (HPA) axis suppression potential for topically applied IDP-118 lotion in pediatric participants with moderate to severe plaque psoriasis.

pituitary
topical agents
plaque psoriasis
  • 11 views
  • 13 Jun, 2022
  • 7 locations
Triamcinolone Acetonide Injections in Mild-to-moderate Chronic Plaque Psoriasis With a Novel Needle-free Drug-delivery System

This is an observational pilot study comparing triamcinolone acetonide injections with the investigational Med-jet needle-free drug-delivery system as an alternative to using a conventional syringe and needle in patients with mild-to-moderate psoriasis. There will be five (5) visits necessary for study participation. The hypothesis is that the efficacy, safety, pain …

plaque psoriasis
  • 0 views
  • 07 Jul, 2022
  • 1 location
An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects (6 to < 18 Years Old) With Severe Plaque Psoriasis

An Open-label, Single-dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Brodalumab in Pediatric Subjects

serum pregnancy test
brodalumab
  • 2 views
  • 22 Sep, 2022
  • 5 locations
Role of Reverse Transcriptase Inhibitors in the Treatment of Psoriasis

The investigators hypothesize that the inhibition of endogenous reverse transcriptase would: (1) reduce excess cytosolic DNA, stress initiating the inflammatory loop at the origin of psoriatic lesions, and (2) interrupt the loop and lighten lesions

plaque psoriasis
  • 0 views
  • 29 Jun, 2021
  • 2 locations