Prostate Disorders Clinical Trials

A listing of Prostate Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 370 clinical trials
Improving Care After Inherited Cancer Testing (IMPACT) Study (IMPACT)

The IMPACT Study seeks to refine and evaluate the effectiveness of interventions on improving guideline-adherent cancer risk management (CRM) and family communication (FC) of genetic test results. These interventions will be delivered to individuals with a documented pathogenic/likely pathogenic (P/LP) variant or variant of uncertain significance (VUS) in an inherited …

Accepts healthy volunteers
cancer
  • 0 views
  • 16 Sep, 2022
  • 1 location
Study to Evaluate CCS1477 in Advanced Tumours

A Phase 1/2a study to assess the safety, tolerability, PK and biological activity of CCS1477 in patients with metastatic castration resistant prostate cancer, metastatic breast cancer, non-small

antiandrogen therapy
bone lesions
solid tumour
androgen
progressive disease
  • 68 views
  • 04 Oct, 2022
  • 22 locations
UV1 Vaccination Plus Nivolumab and Ipilimumab in Treatment of Melanoma

UV1 is a therapeutic cancer vaccine that has been explored in prostate, lung cancer, in combination with ipilimumab in malignant melanoma and in combination with pembrolizumab in metastatic

ipilimumab
metastatic melanoma
cancer
neutrophil count
pembrolizumab
  • 0 views
  • 04 Oct, 2022
  • 36 locations
Prevention of Symptomatic Skeletal Events With Denosumab Administered Every 4 Weeks Versus Every 12 Weeks

The aim of the trial is to test the hypothesis that the benefit of denosumab is maintained if administered only every 12 weeks as compared to every 4 weeks.

ct scan
cancer
bone metastases
calcium
denosumab
  • 75 views
  • 04 Oct, 2022
  • 68 locations
Stereotactic Magnetic Resonance Guided Radiation Therapy

This is a master prospective Phase I-II trial evaluating feasibility and efficacy of stereotactic magnetic resonance (MR) guided adaptive radiation therapy (SMART) in patients with cancer. The phase 1 study will evaluate the feasibility and safety of delivering SMART in patients with cancer. Phase 2 will evaluate efficacy of SMART …

primary cancer
stereotactic body radiation therapy
cancer
  • 0 views
  • 07 Oct, 2022
  • 1 location
Study of the Safety, Tolerability and Efficacy of KPT-8602 in Participants With Relapsed/Refractory Cancer Indications

of the second generation oral XPO1 inhibitor KPT-8602 in participants with relapsed/refractory multiple myeloma (MM), metastatic colorectal cancer (mCRC), metastatic castration resistant prostate

refractory multiple myeloma
cancer
decitabine
dexamethasone
  • 0 views
  • 04 Oct, 2022
  • 34 locations
Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies (PETRA)

This research is designed to determine if experimental treatment with PARP inhibitor, AZD5305, alone, or in combination with anti-cancer agents is safe, tolerable, and has anti-cancer activity in patients with advanced solid tumors.

carboplatin
cancer
parp inhibitor
antineoplastic
chemotherapeutic agent
  • 18 views
  • 07 Oct, 2022
  • 30 locations
Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors

This study is an open-label, international, multi-center, Phase 2 study in adult patients with recurrent, locally-advanced or metastatic solid tumors, which harbor the NRG1 gene fusion.

growth factors
solid tumor
neutrophil count
solid tumors
monoclonal antibodies
  • 0 views
  • 07 Oct, 2022
  • 41 locations
Study of PF-07248144 in Advanced or Metastatic Solid Tumors (KAT6)

This is an open-label, multi center study to evaluate safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of PF-07248144 and early signs of clinical efficacy of PF-07248144 as a single agent and in combination with either fulvestrant or letrozole + palbociclib.

  • 7 views
  • 04 Oct, 2022
  • 27 locations
Study of XL092 in Combination With Immuno-Oncology Agents in Subjects With Solid Tumors (STELLAR-002)

This is a multicenter Phase 1b, open label, dose-escalation and cohort-expansion study, evaluating the safety, tolerability, PK, preliminary antitumor activity, and effect of biomarkers of XL092 administered alone, and in combination with nivolumab (doublet) and nivolumab + ipilimumab (triplet) in subjects with advanced solid tumors. In the Expansion Stage, the …

ipilimumab
measurable disease
cancer
transitional cell carcinoma
programmed cell death 1 ligand 1
  • 0 views
  • 07 Oct, 2022
  • 6 locations