Prostate Disorders Clinical Trials

We are currently recruiting patients for the following: Studies to treat men with Prostate Cancer with/without bone metastasis. A study to treat an enlarged prostate.

Men 45 - 75 years old Urinating often? Weak or hesitant flow? Can't sleep the whole night without having to urinate? Feel your bladder is not completely empty? If you are not interested in taking pills, or if pills do not seem to work, you may be interested in this ...

Do you have any of these symptoms when you urinate? Getting up multiple times during the night to urinate Weak or intermittent stream Straining or waiting for the stream to start Sensation of not emptying your bladder completely Increased frequency or urgency of urination We are conducting a research study ...

This study is being done to see how safe and effective abemaciclib is when given together with abiraterone acetate plus prednisone in participants with metastatic castration resistant prostate cancer. Prednisolone may be used instead of prednisone per local regulation.

Systematic evaluations of functional and cognitive status, comorbidities, health status, mobility, nutritional status, psychological status, and social circumstances as well as measurements of cellular senescence and chronic inflammation will be performed in a cohort of prostate cancer patients at baseline (before radiotherapy), at the end of radiotherapy and at follow-up ...

PRIMARY OBJECTIVE: I. To estimate the proportion of patients who achieve a clinically significant improvement in erectile dysfunction (ED) when treated with a combination of atorvastatin or patient's currently prescribed statin, vitamin E, and pentoxifylline (PAVE). SECONDARY OBJECTIVES: I. To report the safety profile of PAVE. II. To report the ...

Radiation therapy is an accepted treatment to help manage low and intermediate risk prostate cancer. Radiation therapy can be given using machines that are outside the body (called "image guided external beam radiation therapy") or by brachytherapy, which is a form of radiation therapy where the radiation source is placed ...

PINNACLE is a prospective, multi-center, randomized control clinical trial to establish the safety and efficacy of the Optilume BPH Catheter System in the treatment of benign prostatic hyperplasia (BPH)

After performing tumor biopsies and blood collection and processing the biopsies and research blood for comprehensive molecular analysis using established methods for RNA and DNA analysis, we will use Pathway Recognition using Data Integration on Genomic Models (PARADIGM) and Differential Pathway Signature Correlation (DiPSC), computational approaches to pathway activity and ...

This research study is a Phase II clinical trial. Phase II clinical trials test the safety and effectiveness of an investigational drug to learn whether the combination of drugs works in treating a specific disease. "Investigational" means that the drugs are being studied. The FDA (the U.S. Food and Drug ...