Prostate Disorders Clinical Trials

This is a randomized, double-blind, placebo-controlled, multicenter phase III study. The study population will consist of approximately 1300 subjects with metastatic hormone sensitive prostate cancer (mHSPC), who will be randomized (1:1 ratio) to receive 600 mg (2 x 300 mg tablets) of darolutamide (ODM-201)/placebo twice daily with food, equivalent to ...

The ATR(ataxia-telangiectasia and Rad3 related protein) inhibitor BAY1895344 is developed for the treatment of patients with advanced solid tumors and lymphomas. The purpose of the proposed trial is to evaluate the safety and tolerability of BAY1895344, and to identify the maximum tolerated dose of BAY1895344 that could be safely given ...

The relatively restricted C4.4a expression pattern provides a target for the selective delivery of a cytotoxic drug to C4.4.a-expressing tumor cells by means of a suitable antibody-drug conjugate. The subject population eligible for the current study will be those subjects with advanced malignancies known to express C4.4a, which are refractory ...

We are currently recruiting patients for the following: Studies to treat men with Prostate Cancer with/without bone metastasis. A study to treat an enlarged prostate.

Men 45 - 75 years old Urinating often? Weak or hesitant flow? Can't sleep the whole night without having to urinate? Feel your bladder is not completely empty? If you are not interested in taking pills, or if pills do not seem to work, you may be interested in this ...

Do you need to urinate frequently? Do you often have to get up at night to urinate? Is it difficult to start urinating? Do you have a weak stream? Do you feel that your blader is not completely empty? If you answered YES to some of these questions, you may ...

Do you have any of these symptoms when you urinate? Getting up multiple times during the night to urinate Weak or intermittent stream Straining or waiting for the stream to start Sensation of not emptying your bladder completely Increased frequency or urgency of urination We are conducting a research study ...

The purpose of the study is to assess the efficacy, safety, and tolerability of mirabegron versus placebo in men with overactive bladder (OAB) symptoms while taking tamsulosin hydrochloride for lower urinary tract symptoms (LUTS) due to Benign Prostatic Hyperplasia (BPH). At Screening (Visit 1), subjects will enter into a 4-week ...

People with prostate cancer  and cardiovascular Disease are asked to participate in a research study being conducted by Montefiore Medical Center.  

Patients who wish to enroll in a research study should discuss the possibilities with their urologist. The TUCC Clinical Research Department staff remains in constant communication with patients throughout their enrollment in clinical trials. These patients receive all study related medication and procedures at no cost. Participation is voluntary and ...