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Parkinson's Disease Clinical Trials

A listing of Parkinson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (23) clinical trials

The purpose of this study is to see if selegiline and tadalafil (generic for Cialis®) results in an improvement in Erectile dysfunction (ED) in male patients with Parkinson's disease (PD) and moderate ED. Male PD patients who have an incomplete response to tadalafil alone will be given both medications to ...

Phase

Dr. Brad Racette will look at an investigational inhaler method for taking medication for Parkinson’s disease (PD). There are up to 7 outpatient office visits that will take 1 to 5 hours each. Participants will receive study drug or a placebo by an inhaler. Compensation is provided. Risks and benefits ...

Phase

The purpose of this study is to see if the study drug, suvorexant, is safe and effective in treating symptoms of insomnia in people with Parkinson's Disease. It is anticipated that a total of 20 subjects, 30 to 80 years of age, with Parkinson's Disease and symptoms of insomnia will ...

Phase

Dr. Kevin Black will look at the safety and effectiveness of an investigational drug compared to placebo (inactive substance) in the treatment of Parkinson’s disease with psychosis. Participation in this study may last up to 12 weeks. There will be a screening visit lasting about 3 hours and up to ...

Phase

This is a multi-site, placebo-controlled, double-blind, randomized-withdrawal study evaluating the durability of clinical benefit of a study drug for patients with symptomatic neurogenic orthostatic hypotension. This study has a duration of up to 36 weeks, consisting of 5 periods:  Screening Period: up to 4 weeks duration;  Open-Label Titration Period (Titration ...

Phase

Effect of Acetylcholinesterase Inhibitors on the Gait of the Patients With Parkinson Disease

PD patients with PIGD subtype will be included. Assessment: Overall features of PD are assessed by Unified Parkinson Disease Rating Scale (UPDRS). Non-motor features including cognition will be assessed by standard scales. Gait and balance will be assessed by gait analysis system, which measures physiological parameters of gait such as ...

Phase

Fesoterodine on Urgency Episodes in Parkinson's Disease Population

Study purpose and rationale: Patients with Parkinson's disease (PD) commonly develop lower urinary tract symptoms as their disease severity progresses. The most frequent symptoms are nocturia (night time urinary frequency), urinary frequency and urgency. (1) The effects on voiding function of levodopa and dopamine agonists for the treatment of motor ...

Phase

A Randomized Double-Blind Placebo-Controlled Study of Droxidopa for Fatigue in Parkinson's Disease

This is a randomized, double-blind, placebo-controlled trial comparing droxidopa to placebo for fatigue in Parkinson's Disease. The primary outcome measure is change in the Parkinson's Disease Fatigue Scale, a 16-item scale that measures the physical effects of fatigue as well as the impact of fatigue on daily functioning and activities, ...

Phase

Sagene 2014 - Parkinson's Disease and Erectile Dysfunction

The purpose of this study is to see if selegiline and tadalafil (generic for Cialis) results in an improvement in Erectile dysfunction (ED) in male patients with Parkinson's disease (PD) and moderate ED. Male PD patients who have an incomplete response to tadalafil alone will be given both medications to ...

Phase

The Effects of Rasagiline on Cognitive Deficits Associated With Parkinson's Disease

The primary objective of this study is to assess the effects of rasagiline on cognitive deficits in non-demented patients with PD. The secondary objective is to assess affective changes in this patient population. This will be a randomized, double-blind, placebo controlled study in 1-3 centers. Patients will be recruited from ...

Phase