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Parkinson's Disease Clinical Trials

A listing of Parkinson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (34) clinical trials

For most people with Parkinson's doctors use levodopa to manage symptoms. But, with long term treatment, the effectiveness of the levodopa pills often lessens and lead to off episodes, which include slowness, stiffness and tremors. There are few treatment options to manage these off episodes. A treatment approach that permits ...

Phase

This study will evaluate the safety and tolerability of Tozedenant as adjunctive therapy in Levodopa treated patients.

Phase

Parkinson’s disease affects about 1 million people in the United States. Up to 50% of those affected experience daily changes in performing motor activities, called “OFF” episodes. These include periods of time where your medication wears off before the next dose and your Parkinson’s disease symptoms return, a delay in ...

Phase

The purpose of this study is to determine whether the gastric retentive Accordion Pill™ Carbidopa/Levodopa (AP-CD/LD) is more effective than the commercially available immediate release Carbidopa/Levodopa in reducing motor fluctuations such as "off time" in advanced Parkinson's Disease patients.

Phase

A 24-week, prospective, multi-center, open-label, Phase 3 study in L-Dopa responsive PD patients with motor fluctuations ("OFF" episodes), designed to evaluate the long-term safety, tolerability and efficacy of APL-130277.  

Phase

A 24-week, prospective, multi-center, open-label, Phase 3 study in L-Dopa responsive PD patients with motor fluctuations ("OFF" episodes), designed to evaluate the long-term safety, tolerability and efficacy of APL-130277.  

Phase

A Phase 3, Twelve-week, Multi-Center, Multinational, Randomized, Double-Blind, Double-Dummy, Parallel Group Study to Determine the Efficacy, Safety and Tolerability of P2B001 Once Daily Compared to its Individual Components in Subjects With Early Parkinson's Disease and to a Calibration Arm of Pramipexole ER.  

Phase

This is a Phase 3, 12-week, multi-Center, multi-national, randomized, double-blind, double-dummy, parallel-group study to determine the effectiveness, safety and tolerability of P2B001 taken once daily compared to its individual components in adults with early Parkinson's disease (PD) and to a calibration arm of Pramipexole ER. A total of 525 eligible ...

Phase

To evaluate the safety and efficacy of IPX203 (carbidopa and levodopa) extended-release capsules (IPX203 ER CD-LD) in comparison to immediate release (IR) CD-LD in the treatment of CD-LD-experienced subjects with Parkinson's disease (PD) who have motor fluctuations.  

Phase