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Parkinson's Disease Clinical Trials

A listing of Parkinson's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (609) clinical trials

Parkinson’s disease affects about 1 million people in the United States. Up to 50% of those affected experience daily changes in performing motor activities, called “OFF” episodes. These include periods of time where your medication wears off before the next dose and your Parkinson’s disease symptoms return, a delay in ...

Phase

Dr. Kevin Black will look at the safety and effectiveness of an investigational drug compared to placebo (inactive substance) in the treatment of Parkinson’s disease with psychosis. Participation in this study may last up to 12 weeks. There will be a screening visit lasting about 3 hours and up to ...

Phase

Primary Objective: To compare the pharmacokinetics (PK) of single and multiple doses of IPX203 with Immediate release carbidopa-levodopa (IR CD-LD) in subjects with advanced Parkinson's disease (PD). Secondary Objectives: To compare the pharmacodynamics of single and multiple doses of IPX203 with IR CD-LD. To compare the efficacy of IPX203 with ...

Phase

The purpose of the study is to determine how quickly a protein called Alpha-synuclein (a-syn) is cleared from the body in participants with Parkinson’s disease. A-syn is a major component of Parkinson’s disease. There are up to 7 study visits. Participation includes neurological/physical exam, vitals, blood draws and lumbar puncture ...

Phase N/A

The study will involve an eighteen-week, double-blind, placebo-controlled parallel designed comparison between add-on topiramate and add-on placebo to stable treatment with amatadine in the treatment of PD patients who continue to have dyskinesia on amantadine.

Phase

The purpose of this study is to assess the effect of CK-2127107 versus placebo on respiratory function and other measures of skeletal muscle function in patients with ALS.

Phase

The purpose of this study is to determine whether the gastric retentive Accordion Pill™ Carbidopa/Levodopa (AP-CD/LD) is more effective than the commercially available immediate release Carbidopa/Levodopa in reducing motor fluctuations such as "off time" in advanced Parkinson's Disease patients.

Phase

A clinical research study is underway, evaluating an investigational study drug for adults with Parkinson's Disease who are experiencing a decline in memory and thinking.

Phase

The primary objective is to understand the utility of Personal KinetiGraph movement recording system data in the clinical management of Parkinson's disease (PD) in routine clinical care at a movement disorders clinic. Specifically: 1. Measure medication use and clinical management plan changes in a large, multicenter cohort among participants undergoing ...

Phase N/A