Pancreatic Disorders Clinical Trials

A listing of Pancreatic Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 32 clinical trials
Combination of Anti-PD-1 Antibody and Chemotherapy in Pancreatic Cancer

The prognosis of pancreatic cancer is extremely poor. Current guidelines recommend FOLFIRINOX or modified-FOLFIRINOX as the first-line chemotherapeutic regimen. Studies have shown that immunotherapy with Anti-PD-1 antibody can effectively increase the response rate and prolong patient survival in a number of cancer diseases. Here investigators intend to compare the therapeutic …

adenocarcinoma
platelet count
monoclonal antibodies
breast ductal carcinoma
cancer chemotherapy
  • 23 views
  • 29 Jul, 2021
  • 1 location
A Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Who Are Homozygous for F508del, Heterozygous for F508del and a Gating (F/G) or Residual Function (F/RF) Mutation, or Have At Least 1 Other Triple Combination Responsive (TCR) CFTR Mutation and No F508del Mutation

The purpose of this study is to evaluate the efficacy and safety of VX-121/tezacaftor/deutivacaftor (VX-121/TEZ/D-IVA) in CF participants who are homozygous for F508del, heterozygous for F508del and a gating (F/G) or residual function (F/RF) mutation, or have at least 1 other TCR CF transmembrane conductance regulator (CFTR) gene mutation and …

fibrosis
tezacaftor
forced expiratory volume
cftr gene
  • 0 views
  • 16 Jan, 2022
  • 13 locations
18F-DOPA II - PET Imaging Optimization

A single centre non-randomized, non-blinded phase III prospective cohort study of 18F-DOPA PET/CT imaging in specific patient populations: Pediatric patients (less than 18 years old) with congenital hyperinsulinism. Pediatric patients (less than 18 years old) with neuroblastoma. Pediatric (less than 18 years old) or Adult patients (18 or older) with …

  • 0 views
  • 25 Jan, 2022
  • 1 location
Antibiotic Treatment Of Staphylococcus Aureus In Stable People With CF

This is a randomized, double-blinded study that aims to assess the effect of an oral antibiotic called Cephalexin (150 mg/kg/day) compared to placebo in clinically stable children with cystic fibrosis who have grown a bacteria called MSSA (methicillin-susceptible Staphylococcus aureus) over the course of 2 weeks. A sensitive technique called …

pilocarpine
staphylococcus aureus
fibrosis
antibiotics
cftr gene
  • 0 views
  • 19 Jan, 2022
  • 2 locations
Equivalence Study to Compare Two Strengths of Creon in China

This will be an open-label, randomized, multicenter, cross-over study in 60 subjects with PEI delivering data of 60 subjects for Pancreatin Enteric-Coated Capsules 25000 and of 60 subjects for Pancreatin Enteric-Coated Capsules 10000. The study will be conducted in up to 10 sites in China.

pancreatitis
pancreatectomy
endoscopic ultrasound
cervical cap
bilateral tubal ligation
  • 27 views
  • 02 Dec, 2021
  • 1 location
CHARM II: Chemotherapy for Ablation and Resolution of Mucinous Pancreatic Cysts

The purpose of this study is to evaluate the efficacy and safety of chemotherapeutic pancreatic cyst ablation using ethanol lavage followed by the infusion of a dual-agent chemotherapeutic cocktail (paclitaxel + gemcitabine) compared with alcohol-free saline lavage followed by infusion of the same dual-agent chemotherapeutic cocktail (paclitaxel + gemcitabine) for …

endoscopic ultrasound
paclitaxel
endoscopy
gemcitabine
anesthesia
  • 101 views
  • 18 Dec, 2021
  • 4 locations
Combination of Anti-PD-1 Antibody and Chemotherapy in Metastatic Pancreatic Cancer

The prognosis of pancreatic cancer is extremely poor. NCCN guidelines recommend FOLFIRINOX or modified-FOLFIRINOX as the first-line chemotherapeutic regimen. Studies have shown that immunotherapy with Anti-PD-1 antibody can effectively increase the response rate and prolong patient survival in a number of cancer diseases. Here investigators intend to compare the therapeutic …

adenocarcinoma
gemcitabine
breast ductal carcinoma
cancer chemotherapy
pancreatic ductal adenocarcinoma
  • 11 views
  • 23 Jan, 2021
  • 1 location
Mistletoe Therapy in Primary and Recurrent Inoperable Pancreatic Cancer

In this study a mistletoe preparation (Iscador Qu) is added to standard therapy in inoperable pancreatic cancer in order to evaluate effect on overall survival and health-related quality of life. Half of participants will take subcutaneous injections with mistletoe in addition to standard therapy (palliative chemotherapy or best supportive care); …

ca19-9
metastatic pancreatic cancer
cancer chemotherapy
  • 95 views
  • 15 Jun, 2021
  • 1 location
Carbon Ion RT for Locally Advanced Pancreatic Cancer

This is an open-label randomized trial. Subjects will be randomized in a 2:1 ratio to receive carbon ion radiotherapy versus standard care for locally advanced pancreatic cancer. Subjects who receive carbon ion radiotherapy may receive additional chemotherapy afterwards, at the discretion of the treating physicians. Subjects on the control arm …

  • 0 views
  • 19 Jan, 2022
  • 1 location
A Study to Evaluate ELX/TEZ/IVA on Cough and Physical Activity in Subjects With Cystic Fibrosis (CF)

This study will evaluate the effects of elexacaftor/tezacaftor/ivacaftor (ELX/TEZ/IVA) on cough and physical activity using wearable technology in CF participants.

fibrosis
ivacaftor
tezacaftor
forced expiratory volume
elexacaftor
  • 0 views
  • 19 Jan, 2022
  • 8 locations