Pancreatic Disorders Clinical Trials

A listing of Pancreatic Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 25 clinical trials
Antibiotic Treatment Of Staphylococcus Aureus In Stable People With CF (ASAP-CF)

This is a randomized, double-blinded study that aims to assess the effect of an oral antibiotic called Cephalexin (150 mg/kg/day) compared to placebo in clinically stable children with cystic fibrosis who have grown a bacteria called MSSA (methicillin-susceptible Staphylococcus aureus) over the course of 2 weeks. A sensitive technique called …

methicillin
pilocarpine
staphylococcus aureus
pancreatic enzyme
cftr gene
  • 0 views
  • 25 Mar, 2022
  • 2 locations
CHARM II: Chemotherapy for Ablation and Resolution of Mucinous Pancreatic Cysts (CHARM)

The purpose of this study is to evaluate the efficacy and safety of chemotherapeutic pancreatic cyst ablation using ethanol lavage followed by the infusion of a dual-agent chemotherapeutic cocktail (paclitaxel + gemcitabine) compared with alcohol-free saline lavage followed by infusion of the same dual-agent chemotherapeutic cocktail (paclitaxel + gemcitabine) for …

gemcitabine
anesthesia
cyst
paclitaxel
endoscopic ultrasound
  • 116 views
  • 05 May, 2022
  • 2 locations
Carbon Ion RT for Locally Advanced Pancreatic Cancer

This is an open-label randomized trial. Subjects will be randomized in a 2:1 ratio to receive carbon ion radiotherapy versus standard care for locally advanced pancreatic cancer. Subjects who receive carbon ion radiotherapy may receive additional chemotherapy afterwards, at the discretion of the treating physicians. Subjects on the control arm …

neutrophil count
celiac
chemotherapy drug
cancer chemotherapy
adenocarcinoma
  • 0 views
  • 23 Mar, 2022
  • 1 location
Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age

The purpose of this study is to evaluate the pharmacokinetics, safety, tolerability and efficacy of VX-121/tezacaftor/deutivacaftor (VX-121/TEZ/D-IVA) in CF participants with at least 1 triple combination responsive (TCR) mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

fibrosis
tezacaftor
cftr gene
  • 0 views
  • 10 Aug, 2022
  • 7 locations
Organoid-Guided Adjuvant Chemotherapy for Pancreatic Cancer

The purpose of this study is to explore whether adjuvant chemotherapy regimens guided by organoid drug sensitivity test can improve the outcomes of pancreatic cancer. At the same time, this study will evaluate the successful establishment rate of organoid from fresh surgical specimens , and explore the concordance between drug …

neutrophil count
pancreatic adenocarcinoma
cancer chemotherapy
carcinoma
adenocarcinoma
  • 0 views
  • 08 Aug, 2022
  • 1 location
Testing the Use of the Usual Chemotherapy Before and After Surgery for Removable Pancreatic Cancer

This phase III trial compares perioperative chemotherapy (given before and after surgery) versus adjuvant chemotherapy (given after surgery) for the treatment of pancreatic cancer that can be removed by surgery (removable/resectable). Chemotherapy drugs, such as fluorouracil, irinotecan, leucovorin, and oxaliplatin, work in different ways to stop the growth of tumor …

oxaliplatin
neutrophil count
cancer chemotherapy
drainage
ct scan
  • 193 views
  • 26 Jan, 2021
  • 179 locations
Perioperative or Adjuvant mFOLFIRINOX for Resectable Pancreatic Cancer (PREOPANC-3)

The PREOPANC-3 study is a randomized, multicenter, phase 3 trial. Patients with resectable pancreatic cancer will be randomly assigned (1:1) to 8 cycles of neoadjuvant mFOLFIRINOX followed by surgery and 4 cycles of adjuvant mFOLFIRINOX (arm 1) or to upfront surgery followed by 12 cycles of adjuvant mFOLFIRINOX (arm 2). …

EGFR
oxaliplatin
resectable pancreatic cancer
cancer chemotherapy
leucovorin
  • 0 views
  • 07 Jul, 2022
  • 15 locations
The Impact of Thromboprophylaxis on Progression Free Survival of Patients With Advanced Pancreatic Cancer (imPaCT-PRO)

This is a prospective, randomized, multicenter, open-label, blinded-endpoint Phase III clinical trial to investigate the impact of thromboprophylaxis using innohep, beyond anticoagulation in the improvement of the clinical outcomes in active pancreatic cancer patients receiving systemic anti-neoplasmatic treatment. The number of patients that will be enrolled is 450. The enrollment …

gemcitabine
tinzaparin
cancer
cancer chemotherapy
paclitaxel
  • 0 views
  • 23 Apr, 2022
  • 1 location
Timing of Start of systemIc Treatment for Asymptomatic Metastasized Pancreatic Cancer

Since patients with metastatic pancreatic cancer have a limited life expectancy, it is important to determine the timing of when to start chemotherapy in order to optimize the benefits of chemotherapy relative to the side effects. Therefore, two treatment strategies can be considered: chemotherapy started immediately at diagnosis, or delayed …

  • 0 views
  • 31 May, 2021
  • 1 location
Simultaneous Resection of Pancreatic Cancer and Liver Oligometastasis After Induction Chemotherapy

This study is a multi-center phase 3 trial to evaluate a treatment strategy for selecting patients who can benefit from the synchronous resection of primary pancreatic cancer and liver oligometastasis after induction chemotherapy. Half of participants who meet the entry criterion will receive surgical intervention, while the other half will …

gemcitabine
oxaliplatin
cancer
cancer chemotherapy
fluorouracil
  • 8 views
  • 15 Feb, 2022