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Pancreatic Disorders Clinical Trials

A listing of Pancreatic Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (19) clinical trials

Perioperative MVT-5873 a Fully Human Monoclonal Antibody Against a CA 19-9 Epitope for Operable CA 19-9 Producing Pancreatic Cancers Cholangiocarcinomas and Metastatic Colorectal Cancers

Background Resections to remove tumors in the liver, bile ducts and pancreas are rarely curative, and patients frequently succumb to disease recurrence in the ensuing months to year(s) after the operation. Standard adjuvant therapies, which typically begin 6-12 weeks after surgery, offer little demonstrable decreases in the rates of tumor ...

Phase

Cystic Fibrosis and Cognitive Function

A growing body of evidence suggests that hyperglycemia in type 1 and type 2 diabetes is associated with alterations in brain structure and cognitive impairment. People with cystic fibrosis related diabetes (CRFD) are exposed to hyperglycemia as seen in other forms of diabetes, and cystic fibrosis is also associated with ...

Phase N/A

Gut Imaging for Function & Transit in Cystic Fibrosis Study 2

This is a small pilot study to compare the effects of active drug (Tezacaftor/Ivacaftor with Ivacaftor) on the gut in people with CF. Participants will be randomised to take active drug or matched placebo for 28 days then switch to the alternate drug after a 28 day washout period. Before ...

Phase

EUS-guided Through-the-needle Microforceps Biopsy Outcomes

Recently, a EUS-guided through-the-needle microforceps device (Moray Micro Forceps, US Endoscopy, Mentor, Ohio, United States), witch can be passed through the lumen of a 19-gauge FNA needle, has been introduced as a novel approach for PCLs tissue acquisition. It has been shown that this device can drastically changed the diagnosis, ...

Phase N/A

Digital Catheter Based Pancreatoscopy (SpyGlassDS) for the Management of Symptomatic Pancreatic Duct Stones in Selected Patients With Chronic Pancreatitis

Background Endoscopic treatment of patients with chronic calcifying pancreatitis (CCP) is still challenging and controversially discussed. The goal is symptom control and relief of pain, which can be achieved by draining an obstructed main pancreatic duct (MPD) and/or removal of ductal stones. The 2012 European Society of Gastrointestinal Endoscopy (ESGE)- ...

Phase N/A

Comparison of Standard and Endoscope Assisted Endotracheal Intubation

Endoscopic Retrograde Cholangiopancreatography (ERCP) procedures are typically performed using general anesthesia. During anesthesia, the anesthesiologist inserts a breathing tube (endotracheal tube) into the patient's wind pipe (trachea) and a machine helps the patient breathe (mechanical ventilation) while they are unconscious. The breathing tube is inserted with a patient laying on ...

Phase N/A

A Study Evaluating the Long-term Safety of VX-445 Combination Therapy

This study will evaluate the long-term safety and tolerability of elexacaftor (ELX, VX-445) in triple combination (TC) with tezacaftor (TEZ) and ivacaftor (IVA).

Phase

Parenting Concerns in Patients With Cystic Fibrosis (MucoPar)

Life expectancy has improved significantly in cystic fibrosis in recent years. From paediatric disease, it has become a disease of the adult, with the emergence of new issues, such as becoming a parent. Parent patients still face the risk of complications and death while their child is still young. However, ...

Phase N/A

A Study of SGN-CD228A in Advanced Solid Tumors

This study is designed to evaluate the safety, tolerability, PK, and antitumor activity of SGN-CD228A in select advanced solid tumors. The study will include dose escalation and dose expansion, with multiple disease-specific expansion cohorts.

Phase

PRIMUS 001: A Study Looking at Two Different Chemotherapy Regimens in Patients With Metastatic Pancreatic Cancer

PRIMUS 001 is a multicentre, randomised, open label, two arm, phase II interventional trial with pre-clinical and translational work including in-depth molecular profiling and biomarker discovery/development. The primary objective is to look at the efficacy of FOLFOX-A compared to AG in all comers and in a biomarker positive group using ...

Phase