Frontotemporal Dementia Clinical Trials
A listing of Frontotemporal Dementia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 76 clinical trials
NEO-SPACE Trial: Pembrolizumab and Chemoradiation in Nasopharyngeal Cancer
This is an open label, single arm, non-randomized, multi-site, phase 2 clinical trial of neoadjuvant pembrolizumab in combination with gemcitabine-cisplatin for 2 cycles,followed by concurrent pembrolizumab-cisplain-radiation, and then maintainence pembrolizumab monotherpy given every 3 weeks for a total treatment duration of 12 months, in previously untreated stage IVA ( UICC …
- 54 views
- 29 May, 2022
- 1 location
Cisplatin-based and Carboplatin-based Chemoradiation in Locoregionally Advanced Nasopharyngeal Carcinoma
The purpose of this study is to compare cisplatin-based with carboplatin-based chemoradiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma (NPC), in order to confirm the value of carboplatin-based chemoradiotherapy in NPC patients.
- 66 views
- 03 Feb, 2022
- 1 location
Validation of Serum Neurofilament Light Chain as a Biomarker to Differentiate Cognitive Impairment From Neurodegenerative or Psychiatric Diseases (Nfl_COG)
The validation of biomarkers allowing the discrimination of cognitive and behavioral disorders of psychiatric origin from those of neurodegenerative origin would facilitate diagnosis and improve patient management. Neurofilaments, which are markers of neuronal lysis, appear to be a promising biomarker. In a previous preliminary study, the investigators demonstrated significantly lower …
- 0 views
- 21 Oct, 2022
- 2 locations
OCT-Angiography and Adaptive Optics in Patients With Memory Impairment (OCTAVO)
cognitive impairment), or to other neurodegenerative diseases such as frontotemporal dementia or Lewy body diseases. These retinal anomalies objectified by OCT-A (Optical coherence tomography
- 28 views
- 04 Oct, 2022
- 1 location
Treatment for Speech and Language in Primary Progressive Aphasia
Primary progressive aphasia (PPA) is a progressive neurological disorder that causes a gradual decline in communication ability as a result of selective neurodegeneration of speech and language networks in the brain. PPA is a devastating condition affecting adults as young as their 40's or 50's, depriving them of the ability …
- 0 views
- 14 Apr, 2022
- 2 locations
PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel TSPO Radioligand
Background Aging-related progressive neurological disorders include frontotemporal dementia, Lou Gehrig s disease, and Alzheimer s disease. Little is known about
- 28 views
- 20 Oct, 2022
- 1 location
The Influence of Vascular Burden, Amyloid Plaque and Tau Protein in Patients With Vascular Cognitive Impairment and Dementia With Tauopathy
with vascular cognitive impairment (VCI) (Group A, n=200), Alzheimer's disease/mild cognitive impairment (MCI) (Group B, n = 200), and fronto-temporal dementia (FTD) (Group C, n =30). In addition
- 0 views
- 02 Mar, 2022
- 1 location
Phase 1 Study: PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
health who have an adult-onset neurodegenerative dementia, such as AD, FTD, corticobasal syndrome, or Huntington s disease and healthy adult volunteers enrolled in protocols 01-M-0254 or 17-M-0181.
- 27 views
- 23 Oct, 2022
- 1 location
TAS-102 in Extrapulmonary Neuroendocrine Carcinoma (TAS-102 NEC)
The purpose of this study is to test the safety and efficacy of drug, TAS-102 (trifluridine/tipiracil), in patients with extrapulmonary (outside the lung) high-grade neuroendocrine cancer. TAS-102 demonstrated improved survival and tolerability in patients with colorectal cancer and is currently approved by the FDA and marketed under the brand name …
- 99 views
- 24 Feb, 2022
- 1 location
Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer
This phase I trial investigates the side effects and best dose of talazoparib when given together with trifluridine/tipiracil for the treatment of patients with colorectal or gastroesophageal cancer that has spread to nearby tissue or lymph nodes (locally advanced) or other places in the body (metastatic). Drugs used in the …
- 0 views
- 08 Mar, 2022
- 1 location