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Alzheimer's Disease Clinical Trials

A listing of Alzheimer's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (122) clinical trials

Optical Coherence Tomography in Cerebral Amyloidosis

Being a direct extension of the central nervous system and the only place in the human body where the vessels of the central circulation can be visualized directly, the eye provides a unique window to investigate the central circulatory system. Several studies have demonstrated that retinal blood vessels show structural ...

Phase N/A

Comprehensive Assessment of Neurodegeneration and Dementia

This is a 5-year observational study. Sixteen-hundred and fifty (1650) subjects, between the ages of 50 and 90,years old, with Subjective Cognitive Impairment, Mild Cognitive Impairment, Mild Cognitive Impairment with subcortical vascular lesions, Alzheimer's Disease, Mixed dementia, Lewy Body Dementia, Parkinson's Disease Dementia, Parkinson's Disease with Mild Cognitive Impairment and ...

Phase N/A

The University of Hong Kong Neurocognitive Disorder Cohort

The HKU Neurocognitive Disorder (NCD) Cohort is a hospital-based, prospective, observational study of older HK Chinese adults with cognitive impairment, with a special focus on studying patients with subjective cognitive decline and mild cognitive impairment, and in particular the biomarkers that predict cognitive and functional decline. Comprehensive profiling of each ...

Phase N/A

Diagnosis of Alzheimer's Disease Using Event Related Potentials

The objective of this study is to improve the accuracy of diagnosis of Alzheimer's disease in a clinic setting using an EEG device to measure event related potentials. This study will recruit patients who are being seen with a memory complaint or the first time. It will be prospective in ...

Phase N/A

Biomarker Study for Alzheimer's Disease

Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by the loss of cognitive brain functions and functional decline. One of the pathological features of this condition is the progressive deposition in the brain of amyloid beta-peptide (A-beta) (1). Once deposited in the brain, the peptide exerts a toxic effect ...

Phase N/A

A Retrospective Study to Investigate the Additive Effectiveness of Chinese Herbal Medicine in Alzheimer's Disease

Conventional therapy (CT), such as donepezil and memantine are well- known short-term treatments for the symptoms of Alzheimer's disease (AD). The efficacy of them, however, drops below baseline level after 9 months. Should Chinese herbal medicine make add-on benefit? The GRAPE formula was designed by Prof. J Tian, a prepared ...

Phase N/A

Alzheimer's Disease Core Center

All participants are seen annually. In addition to a detailed neurological examination, participants will receive a standardized battery of neuropsychological tests and will undergo genetic testing. The investigators will provide standardized periodic longitudinal assessment of the research participants. Autopsies to establish neurohistopathological diagnoses in clinically well-characterized patients with dementia, patients ...

Phase N/A

Behavioral and Environmental Sensing and Intervention

The dementia syndrome of Alzheimer's disease and other disorders is rapidly expanding due to the aging of society and the longevity of citizens. In its varying stages, care of the dementia syndrome requires differing sets of skills from the caregivers, and more skilled intervention is required as the disease progresses. ...

Phase N/A

Research on the Early and Prognosis Diagnosis of Vascular Dementia

Around 10% of stroke survivors develop dementia within 3 months after stroke and over 20% more stroke patients have dementia in the subsequent 3 years. Previous studies documented a close relationship between stroke and Alzheimer's disease (AD). There are, however, no reliable biomarkers to detect cognitive dysfunction and dementia among ...

Phase N/A

Identification of Proteostasis-related Biomarkers in Alzheimer s Dementia

Within the last years, protein analyses of A-species in the cerebrospinal fluid (CSF) and amyloid-imaging using F18-based PET-tracers have become a part of the diagnostic repertoire in specialized memory clinics allowing a neurobiological, biomarker-based validation of Alzheimers disease (AD) diagnosis. This has led to a substantial increase in the specificity ...

Phase N/A