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Alzheimer's Disease Clinical Trials

A listing of Alzheimer's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (121) clinical trials

The "Motoric Cognitive Risk" Syndrome in the Canadian Population

Cognition and locomotion are two human abilities controlled by the brain. Their decline is highly prevalent with aging, and is greater than the simple sum of their respective prevalence, suggesting a complex age-related interplay between cognition and locomotion. Recently, a systematic review and meta-analysis has provided evidence that poor gait ...

Phase N/A

Longitudinal Validation of a Computerized Cognitive Battery (Cognigram) in the Diagnosis of Mild Cognitive Impairment and Alzheimer's Disease

Rationale Today's aging population brings an increase in the incidence of dementia. In Canada, there are approximately 564,000 persons diagnosed with dementia, with an expected two-fold increase in this number by the year 2031. In this context, the early detection and prediction of cognitive decline are both imperative for achieving ...

Phase N/A

OCT Angiography and NRAI in Dementia

The primary goals of this study are to use optical coherence tomography (OCT) angiography (blood vessel mapping) to: Detect retinal blood vessel and blood flow changes in participants with dementia. Detect amyloid protein deposits in the retinas of participants with dementia.

Phase N/A

INTERCEPTOR Project: From MCI to Dementia

In the next 8 years a number of phase 2-3 trials will end up which utilize experimental drugs possibly disease modifying for Alzheimer Dementia. They target different disease stages: mild-moderate AD, 'early' AD, MCI prodromic to AD (MCI + for biomarkers heralding progression to AD), pre-symptomatic AD in pathogenetic gene ...

Phase N/A

Cholinergic Markers Alzheimer's Disease

Strategy: Within the framework of the usual management, the investigators propose the protocol to patients who had an assay of the CSF biomarkers with a CSF AD biological profile before the introduction of an IChEs and having accepted Their CSF will stocked in our biobank. Patients will only have additional ...

Phase N/A

CUHK Brain Health Longitudinal Study

For those interested participants, our services coordinator, co-investigator or principal investigator will interview and explain the study in detail and obtain your consent. After signed the consent, the participant should complete the Neuro-QoL (Quality of Life in Neurological Disorders) questionnaire first, either on-site at CUHK Brain Health Centre located at ...

Phase N/A

REspectful CAring for the AGitated Elderly

Two cohorts of 250 patients each will be recruited by six clinical centres endowed with a SCU-B (one cohort) and six centres lacking this structure. The follow-up will last 3 years, during which patients will be visited every 6 months and submitted to a battery exploring the severity of the ...

Phase N/A

Detecting Probable Alzheimer's Disease From Speech Using Linguistical Analysis

This study will investigate the use of linguistic deficits through a computational diagnostic model for the prediction of Mild Cognitive Impairment (MCI) and Probable Alzheimer's disease (PrAD) from speech samples (verbal utterances). The premise is that MCI and PrAD are characterized by the deterioration of nerve cells that control cognitive ...

Phase N/A

A Systems Approach to Falls and Discharge Planning

Background: The Care Quality Commission (2016) notes that the Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust (RBCH) has implemented a number of initiatives aimed at improving care given to people with dementia. However, feedback from patients with dementia indicate that improvements are still required (Care Quality Commission, 2016). Therefore, ...

Phase N/A

Down Syndrome Clinical Trials - Study of Alzheimer's Disease in Down Syndrome

Adults with DS face a markedly increased risk of Alzheimer's Disease (AD). DS, the most common genetic cause of AD, is due to trisomy for all or part of a third copy of chromosome 21. It is typically associated with the presence of a number of abnormal clinical phenotypes, including ...

Phase N/A