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Alzheimer's Disease Clinical Trials

A listing of Alzheimer's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (597) clinical trials

Movement Intervention for Memory Enhancement

Social dancing is a complex sensorimotor rhythmic activity integrating physical, cognitive and social elements with the potential to ameliorate a wide range of physical and cognitive impairments in older individuals at risk of Alzheimer's disease (AD) and related dementias. The few extant studies report that dancing stimulates multiple cognitive processes, ...

Phase N/A

Light and the Effect on Metabolic Syndrome and Alzheimer's Disease

Alzheimer's disease (AD) and type 2 diabetes (T2DM) pose linked, major threats to aging societies worldwide, but the relationship between these two diseases remains poorly understood. Hence, insulin resistance may account for the close epidemiological association between AD and T2DM. A major gap in the understanding of this association, however, ...

Phase N/A

Study to Evaluate Amyloid in Blood and Imaging Related to Dementia

Alzheimer's disease is the most common cause of dementia and currently has no disease-modifying treatments or simple, accurate diagnostic tests. Amyloid beta builds up in the brain and forms plaques in people with Alzheimer's disease, and the buildup of this protein is found decades before symptoms of dementia begin. A ...

Phase N/A

Mediterranean Diet Exercise and Dementia Risk in UK Adults

In MedEx-UK the investigators propose to conduct a feasibility study in three UK centres (Norwich, Birmingham, Newcastle) which collectively will recruit 108 UK older adults (55-74y) who are at above average risk of dementia, but pre-clinical. Primary outcome is to evaluate the feasibility of a multi-domain intervention to increase MDP ...

Phase N/A

Identifying Novel Aging Targets for Treatment of Delirium

The study team will recruit patients with no known history of dementia for enrollment into the cohort during their hospital stay for acute respiratory failure. The cohort will undergo testing including cognitive testing, MRI imaging, lumbar puncture for cerebrospinal fluid (CSF) analysis at 3 months following hospital discharge. The study ...

Phase N/A

Brain Energy Metabolism and Sleep in Adults

Alzheimer's disease (AD) is rapidly progressing in the elder population and the pathophysiological changes in the brain start at least 1-2 decades before the disease onset. During this period of slow progression, individuals may notice subtle changes in the memory and this subset of the population is termed as Mild ...

Phase N/A

High Dose Omega 3 in People at Risk for Dementia

Earlier trials with eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been moderately promising, but these interventions often suffered from relatively low DHA concentrations. In this trial, the investigators will use a DHA-rich dietary supplement formulated using a self-microemulsifying delivery system to accelerate absorption. Modification of innate immune activity has ...


A Study of RO7105705 in Patients With Moderate Alzheimer's Disease

This Phase II, multicenter, randomized, double-blind, placebo-controlled, parallel-group study will evaluate the clinical efficacy, safety, pharmacokinetics, and pharmacodynamics of RO7105705 in patients with moderate AD. The study consists of a screening period, a double-blind treatment period, an optional open-label extension (OLE) period, and a safety follow-up period.


EPIC: An Intervention for Early-stage AD Dyads

The purpose of this study is to help early-stage individuals who have early-stage memory loss or early stage dementia and their current or future care partners by providing education and skill-training programs designed to reduce stress and distress, increase well-being and quality of life, and plan for the future. About ...

Phase N/A

The Role of Concomitant Diseases in Postoperative Complications Risk Stratification.

Advances in modern anesthesiology have significantly reduced the risk of anesthesia compared to the last century, however, the level of perioperative hospital mortality of planned operations at the moment is on average about 0.5% (ISOS group, 2016). Weiser et al. (2016) estimated that more than 313 million adults worldwide are ...

Phase N/A