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COVID-19 Clinical Trials

A listing of COVID-19 medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (301) clinical trials

Pathogenesis of BTK-mediated Hyper-Inflammatory Responses in COVID-19 (RESPOND)

Coronavirus disease 2019 (COVID-19) is an acute respiratory syndrome caused by the novel coronavirus severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Severe COVID-19 infection is associated with a hyper-inflammatory response and evidence of innate immune cell activation. Bruton tyrosine kinase (BTK) plays a central role in innate immune cell signaling and …

Phase N/A

Study on the Recovery of Pulmonary Function Chest CT Hematologic and Immune & Inflammatory Conditions in COVID-19 Rehabilitation Patients

About 20% of COVID-19 developed into a critical illness and about 2% died. The global epidemic continues to develop, but some patients in China have entered the rehabilitation period, which is accompanied by a large number of respiratory symptoms and pulmonary fibrosis, bringing serious harm to the country.Therefore, early accurate …

Phase N/A

PRactice of VENTilation in COVID-19 Patients (PRoVENT-COVID)

Rationale The novel coronavirus disease (COVID-19) pandemic is rapidly expanding across the world, with over 60.000 new cases each day as of late March 2020. Healthcare workers are struggling to provide the best care for patients with proven or suspected COVID-19. Approaches for clinical care vary widely between and within …

Phase N/A

Preeclampsia-like Syndrome Induced by COVID-19: Is it a Real Public Health Issue in Pregnancy During the Pandemic?

The investigators studied the frequency of Covid-19 related preeclampsia-like syndrome by PCR test and lung ultrasound for Covid-19 to preeclampsia patients presenting to the instutution during the Covid-19 pandemic period. The first consecutive 100 preeclampsia patients presented to our hospital during the pandemic will be involved in our study. The …

Phase N/A

Effect of COVID-19 Pandemic on Perceived Stress Anxiety Mood and Training Quality in Elite Athletes.

The 2019 coronavirus disease (COVID-19) outbreak started in Wuhan province, China, and rapidly spread into the whole world starting with Europe. On 11 March 2020, the World Health Organization declared the COVID-19 outbreak as a pandemic. On the same day, the first COVID-19 case reported in Turkey and nationwide quarantine …

Phase N/A

Saliva/Nares as Source of Detection for SARS-CoV-2 at NIH

Study Description: This is a prospective sample collection study to validate saliva or nasal swab as a source of detection for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) virus. The potential of saliva coupled with a nasal swab to serve as a detection source will also be investigated. We will collect expectorated …

Phase N/A

Surveillance of Individuals Following SARS-CoV-2 Exposure

Study Description: This is a prospective longitudinal cohort study of contacts of individuals with exposure to severe acute respiratory syndromecoronavirus-2 (SARS-CoV-2). The aim is to correlate results of reverse transcriptionpolymerase chain reaction (RT-PCR) using various sample types, assays, and culture. We will perform serial screenings of NIH employees who have …

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A Longitudinal Study of COVID-19 Sequelae and Immunity

Coronavirus disease-2019 (COVID-19) is a newly recognized viral disease primarily involving the respiratory tract. The world is currently experiencing COVID-19 pandemic with a significant portion of those infected developing severe disease manifestations including pneumonia, acute respiratory distress syndrome with respiratory failure, and, in some cases, death. The clinical characteristics and …

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Risk Prediction and Therapy Monitoring in Patients With SARS-Cov-2 Infection / COVID 19

Approximately 15% of patients with SARS-CoV-2 infection / COVID-19 develop a severe clinical course. This leads to hospitalization and potentially life threatening complications such as pneumonia and respiratory failure. Predictors for early detection and risk stratification are urgently needed. Moreover, only scarce information is available for long-term follow-up and late …

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Genetics of COVID-19 Susceptibility and Manifestations

The current SARS-CoV-2 pandemic presents a serious challenge to public health. Individuals infected with SARS-CoV-2 experience extremes in symptomatology ranging from a complete lack of symptoms to rapidly worsening end-stage pulmonary disease. The explanatory mechanism underlying susceptibility to severe disease remains unknown. We hypothesize that underlying genetic factors are at …

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