Lewy Body Dementia Clinical Trials

A listing of Lewy Body Dementia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 67 clinical trials
NYX-458 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's Disease or Lewy Body Dementia (Cognition Memory Attention Thinking)

A Study to Evaluate NYX-458 in Subjects With Mild Cognitive Impairment or Mild Dementia Associated With Parkinson's Disease or Prodromal or Manifest Lewy Body Dementia

mild dementia
cognitive impairment
cognitive assessment
dementia
parkinson's disease
  • 25 views
  • 17 Sep, 2021
  • 29 locations
Innovations in Dementia Empowerment and Action

The lack of efficacious research-based interventions for such vulnerable older adults with Alzheimer's disease and related dementias (AD/RD) and their caregivers (CGs) is a significant public health problem. Caregiving of sexual/gender minority older adults with AD/RD is of concern due to social stigma, marginalization, and isolation, which may be barriers …

psychiatric disorder
alzheimer's disease
stroke
dementia
behavioral symptoms
  • 5 views
  • 18 Apr, 2021
  • 1 location
[18F]F-DOPA Imaging in Patients With Autonomic Failure

), Multiple System Atrophy (MSA), Dementia with Lewy Bodies (DLB). Common to these disorders are the involvement of the central and peripheral autonomic nervous system, where Pure Autonomic Failure (PAF) is

nervous system disorder
dopamine
atrophy
synucleinopathy
alpha-synuclein
  • 19 views
  • 13 Mar, 2021
  • 1 location
OCT-Angiography and Adaptive Optics in Patients With Memory Impairment

Studies suggest an association between retinal abnormalities and NCD (Neuro Cognitive Disorders) whether they are linked to proven or prodromal Alzheimer's disease (aMCI : amnestic mild cognitive impairment), or to other neurodegenerative diseases such as frontotemporal dementia or Lewy body diseases. These retinal anomalies objectified by OCT-A (Optical coherence tomography …

cognitive impairment
memory impairment
neurodegenerative disorder
optical coherence tomography
cognitive disorder
  • 22 views
  • 25 Jul, 2021
  • 1 location
PST for Care Partners of Adults With Alzheimer's and Alzheimer'S-related Dementia

Caregivers of individuals with Alzheimer's disease and related dementia rarely get the preparation or training they need to manage their caregiving responsibilities and to successfully balance their own self-care and their caregiving roles. As a result, caregivers often experience caregiver burden, emotional distress, and substance abuse. Therefore, there is a …

alzheimer's disease
dementia
  • 0 views
  • 29 Jul, 2021
  • 2 locations
Relationship Between Alzheimer Disease and Diminution of the Three Macular Nervous Retinal Layers

Alzheimer disease is hard, long and expensive to diagnose. In order to help the clinician, a new biomarker in Alzheimer disease seems to be very useful. The retina, as a window of the brain, could offer a new way to diagnose this common disease. Indeed, a retinal atrophy could especially …

  • 1 views
  • 29 Apr, 2021
  • 1 location
ENhancing Outcomes in Cognitive Impairment Through Use of Home Sleep ApNea Testing

Obstructive sleep apnea (OSA), which causes abnormal pauses in breathing during sleep, is common in patients with vascular cognitive impairment (VCI) and Alzheimer's disease (AD), and exacerbates the cognitive deficits seen in these conditions. OSA is typically treated with continuous positive airway pressure (CPAP), which has been shown to improve …

vascular dementia
parkinson's disease
cognitive decline
apnea test
cognitive assessment
  • 2 views
  • 25 Jan, 2021
  • 1 location
Virtual Individual Cognitive Stimulation Therapy: a Proof of Concept Study

Due to COVID-19, the routine treatment for dementia, Cognitive Stimulation Therapy (CST), is currently suspended in multiple countries. Access to treatment is, therefore, paramount. The investigators seek to bridge the current treatment gap with a virtual and individual form of CST, called Virtual Individual Cognitive Stimulation Therapy (viCST). This psychosocial …

cognitive stimulation
moderate dementia
dementia
  • 0 views
  • 12 Aug, 2021
  • 1 location
Inhibition of -synuclein Cell-cell Transmission by NMDAR Blocker Memantine

Lewy Body Dementia (LBD), is the second most common form of dementia after Alzheimer's Disease. Dementia is defined as a serious loss in cognitive ability due to damages or disease in the brain

nervous system disorder
dementia
  • 0 views
  • 25 Jan, 2021
  • 1 location
Clinical Laboratory Evaluation of Chronic Autonomic Failure

Background The autonomic nervous system controls automatic body functions. Researchers want to improve the tests used to diagnose autonomic failure. Orthostatic hypertension is a drop in blood pressure when a person stands up. Researchers want to focus on this sign of autonomic failure. Objective To improve testing for conditions that …

dopamine
cardiac symptoms
sympathectomies
desipramine
ct scan
  • 93 views
  • 01 Aug, 2021
  • 1 location