Osteoarthritis Clinical Trials

A listing of Osteoarthritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 40 clinical trials
The Use of Venlafaxine in Reducing Pain in Primary Total Knee Replacement

Patients experience pain after their knee replacement surgery - and some may continue to experience persistent pain long after their knee replacement surgery. Traditional pain management strategies reply on pain medication such as opioids for pain control. However, these drugs do not work well for pain associated with movement or …

opioid use
nerve block
opioid
total knee replacement
pain relieving
  • 0 views
  • 03 Sep, 2021
  • 1 location
Conditioning Brain Responses to Improve Thigh Muscle Function After Anterior Cruciate Ligament Reconstruction

The purpose of this study is to examine if thigh muscle weakness and the lack of muscle activation that accompanies ACL injury can be improved through a form of mental coaching and encouragement, known as operant conditioning.

reconstructive surgery
weakness
ligament reconstruction
  • 26 views
  • 15 Sep, 2021
  • 1 location
Phase I/II Study of the Anti-Programmed Death Ligand-1 Antibody MEDI4736 in Combination With Olaparib and/or Cediranib for Advanced Solid Tumors and Advanced or Recurrent Ovarian Triple Negative Breast Lung Prostate and Colorectal Cancers

Background MEDI4736 is a drug that may help people s immune systems respond to and kill cancer cells. Olaparib is a drug that may inhibit repairing DNA damage of cancer cells. Cediranib is a drug that may stop the blood vessel growth of cancer cells. This study has two components. …

BRAF
breast cancer
unstable angina
fallopian tube
BRCA1
  • 31 views
  • 15 Sep, 2021
  • 1 location
Behavioral Mechanism of Energy Compensation With Exercise

Over 70% of Americans are either overweight or obese, putting them at risk for many chronic diseases including diabetes. Exercise is commonly used as a weight loss and weight loss maintenance strategy. However, exercise-induced weight loss is often much less than expected as individuals compensate for a large portion of …

  • 0 views
  • 15 Sep, 2021
  • 1 location
Outcomes During Digitally Delivered Osteoarthritis Treatment

Objectives: To examine changes in health-related quality of life (HRQL), pain and function among patients with knee or hip osteoarthritis (OA) participating in digitally delivered exercise and

osteoarthritis
  • 0 views
  • 05 Sep, 2021
  • 1 location
Evaluation of Medium Cross-linked Polyethylene With and Without Vitamin E for Total Knee Arthroplasty

Prospective, randomized, single-blind, multinational, long-term study for the evaluation of the clinical outcome, oxidation profile and wear analysis of medium cross-linked Polyethylene with and without Vitamin E for total knee arthroplasty

total knee replacement
  • 0 views
  • 05 Sep, 2021
  • 7 locations
Correlation of the Inflammatory Parameters With Pain and Radiological Findings in Coxarthrosis

Osteoarthritis (OA) is a functional disease with joint degeneration with subchondral and periosteal lesions. Coxarthrosis (or hip osteoarthritis) is an important cause of disability, especially

osteoarthritis
  • 0 views
  • 05 Sep, 2021
  • 1 location
Long Term Follow-Up of KNEE PAIN Patients Accompanying Meniscus Tear

analyzed, and telephone surveys will be conducted for each patient. The survey questions are Numeric rating scale (NRS), Western Ontario and McMasters Universities(WOMAC) Osteoarthritis Index, quality of

  • 0 views
  • 05 Sep, 2021
  • 1 location
Deficit in Quadriceps Voluntary Activation After Anterior Cruciate Ligament Reconstruction: Roles of the "Learned Non-use" Paradigm and the Interhemispheric Inhibition

may persist for years. Moreover, this deficit leads to increased risk of sustaining another knee injury, and increased risk for developing posttraumatic osteoarthritis. At present, neither the optimal

body mass index
ligament tears
osteoarthritis
anterior cruciate ligament reconstruction
  • 0 views
  • 04 Sep, 2021
  • 2 locations
Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain

Background Researchers are interested in how the muscles affect the movement of the knee cap. These muscles may be related to different kinds of knee pain that are not caused by an injury or a disease. Imaging studies such as magnetic resonance imaging (MRI) can be used to look at …

knee pain
weakness
  • 22 views
  • 15 Sep, 2021
  • 1 location