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Obesity Clinical Trials

A listing of Obesity medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (1120) clinical trials

Lower Protein Intake and Long-term Risk of Obesity and Cardiovascular Disease

Obesity and its cardiovascular consequences are the most important causes of morbidity and mortality worldwide. Breastfed infants have been shown to have less cardiovascular risk factors in adulthood, which can be partially explained by their slower growth compared to formula fed infants. The primary objective of this study is to ...

Phase N/A

Bariatric Surgery and Pharmacokinetics of Atomoxetine

Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines. These factors are potentially influenced by bariatric surgery. Little is so far known about how gastric bypass and sleeve gastrectomy impacts the biological ...

Phase N/A

Daily Protein Intake Patterns on Energy Metabolism and the Motivation to Snack

The purpose of this study is to determine if consuming 30 g of high-quality protein at each meal can increase fat utilization and shift between-meal snack choices. While the benefits of high-protein diets are well known, little is known about the optimal amount of protein that should be eaten at ...

Phase N/A

Multicenter ESG Trial (MERIT Trial)

Endoscopic Sleeve Gastroplasty (ESG) is an endoscopic minimally invasive weight loss procedure where a commercially available, FDA approved, full-thickness endoscopic suturing device (Overstitch; Apollo Endosurgery, Austin, TX) is used to reduce the stomach volume by 80% through the creation of a restrictive endoscopic sleeve. This is accomplished by a series ...

Phase N/A

Healthy Frio: A Rural Community Partnership to Advance Latino Obesity Research

Obesity is a significant health threat in South Texas, a largely Latino region with one of the most underserved, at-risk populations in the nation. Obesity can start in early childhood and persist lifelong, setting the stage for disease.1-3 Because obesity impairs health-related quality of life and billions are spent to ...

Phase N/A

Neuregulin-1 Lipidomics and Inflammation After Resuscitation From Cardiac Arrest

Neuregulin-1 (NRG-1) is a growth factor that crucially regulates cell resistance to oxidative stress, cell survival and proliferation. In preliminary studies, investigators have found a novel role of NRG-1 in the regulation of pro-inflammatory activation of human mononuclear myeloid cells (monocytes and macrophages). These cells represent the major contributors to ...

Phase N/A

Valued EpiGenetic Glycemic ImprovEments Through Weight Loss

The investigators plan to recruit a total of 200 middle-aged (40-65 years) obese (BMI=30-39.9 kg/m2), sedentary, pre-diabetic participants who will be randomized to either a 18-week dietary weight loss (n=100) followed by a 8-week transition and then 26 weeks of maintenance (Weight Loss group) or a delayed weight loss (Control ...

Phase N/A

The Impact of Time Restricted Feeding (TRF) in Improving the Health of Patients With Metabolic Syndrome

The investigators intend to measure the health impact of a dietary intervention known as time restricted feeding (TRF) on patients with metabolic syndrome (three or more of: increased waist circumference, abnormal cholesterol levels, elevated blood pressure, or elevated blood sugar). The investigators will enroll patients with metabolic syndrome who eat ...

Phase N/A

Bariatric Surgery and Pharmacokinetics of Escitalopram

Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines. These factors are potentially influenced by bariatric surgery. Little is so far known about how gastric bypass and sleeve gastrectomy impacts the biological ...

Phase N/A

Depression & Insulin Sensitivity in Adolescents

There has been rapid escalation of type 2 diabetes (T2D) rates in adolescents. Early-onset T2D (<20y) typically shows a more aggressive course than adult-onset T2D and disproportionately affects girls from disadvantaged, racial/ethnic groups. This group of girls also is at heightened risk for depression, and depression and T2D are linked. ...

Phase N/A