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Obesity Clinical Trials

A listing of Obesity medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (58) clinical trials

A study to evaluate the effect of long-term treatment with Belviq® (Lorcaserin HCI) on the incidence of major adverse cardiovascular events and conversion to Type 2 Diabetes Mellitus in obese and overweight subjects with cardiovascular disease or multiple cardiovascular risk factors. Half of the patients will be randomly assigned to ...

Phase

Dr. Samuel Klein will look at why some obese persons are resistant to developing obesity related metabolic diseases (like diabetes and high cholesterol) while other obese persons do develop these conditions. This study lasts 18 weeks. There will be a medical screening visit, MRI/DXA scans, metabolism studies, biopsies, and a ...

Phase

Reward Mechanisms in Obesity

The study aims to investigate the effects of 3.0 mg of liraglutide on reward brain circuits in human obesity and to better understand its effects on weight loss (in patients without diabetes). According to the study protocol, 70 obese patient will be evaluated at baseline and at 16-week (end of ...

Phase

Oxygen Versus Medical Air for Treatment of CSA in Prader Will Syndrome

The aim of this study is to determine if treatment with Medical Air (21% oxygen in room air) compared to supplemental oxygen (100% oxygen) will lead to similar improvements in the central apnea-hypopnea index (CAHI) for infants with Prader-Willi Syndrome. Despite the vast amount of research investigating the cause of ...

Phase

Liposomal Amphotericin B (AmBisome) Pharmacokinetics Given as a Single Intravenous Dose to Obese Patients (ASPEN)

The overall trial design is a prospective, open-label, non-randomized, single-centre, single-dose, multiple dose level trial, (1 mg/kg and 2 mg/kg). A total of sixteen patients with a BMI 40 kg/m2 undergoing bariatric surgery who receive a pre-surgery dose of AmBisome 1 mg/kg (n=8) or 2 mg/kg (n=8) will be enrolled. ...

Phase

ZIMBA: Clinical Trial in Paediatric Obesity

Study design: A single-center pilot open-label randomized control trial. Population: The study will comprise a total of 60 subjects of both sexes, with pubertal stage 3 according to the Tanner stage, obese according to the IOTF criteria (International Obesity Task Force), diet nave or with failure of weight loss (defined ...

Phase

Modulation of Esophageal Inflammation in Barrett's Esophagus by Omega-3 Fatty Acids

Will oral supplementation with Omega 3 free fatty acids in obese Barrett's esophagus subjects downregulate pro-neoplastic and pro-inflammatory pathways in the esophagus to anti-inflammatory pathway?

Phase

Saxenda: Underlying Mechanisms and Clinical Outcomes

The purpose of this protocol is to investigate the effect of treatment with the study drug Liraglutide, a GLP-1 receptor agonist, on centers of the brain that control appetite and food intake.

Phase

The Effect of GLP-1 Agonists Versus OCs on Reproductive Disorders and Cardiovascular Risks in Overweight PCOS

Groups Experimental treatment: Metformin-GLP-1 Receptor Agonist Therapy. Regular treatment: Metformin-Oral Contraceptive(OC) Therapy. Time Point: Initial treatment; Post-treatment (4w); Post-treatment (8w); Post-treatment (12w); Assess reproductive functions and cardiovascular risk factors.

Phase

Assessment of and Treatment Applied to Food Addiction in a Rural Healthy Behaviors Clinic

Treatment Assignment: Both treatment groups,Those who test positive for and those who test negative for FA (food addiction) will be assigned to one of four treatment arms, IC, MI, MI/P and P. All will receive dietary and exercise information. After consenting, each participant be administered the YFAS to determine their ...

Phase