Obesity Clinical Trials

Obesity is a growing national health problem that now affects over 35% of Americans and is the leading cause of preventable death. Obesity affects all organ systems and contributes to the cause of a multitude of medical problems such as cardiovascular disease, diabetes and sleep apnea [1]. It is defined ...

Researchers at the University of Kentucky are currently enroll ing participants in a research study investigating the effects of strength training on movement patterns and physical function in people with obesity. Participants will perform patterns and physical function will be measured before and after the strength training program.

This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group study in overweight and obese subjects with CV disease and/or multiple CV risk factors.

The purpose of the trial is to investigate the effect and safety of liraglutide 3.0 mg as an adjunct to intensive behaviour therapy for obesity in a non-specialist setting.

Researchers at the University of Kentucky are conducting a study to learn whether the 24-hour blood pressure rhythm is affected by timing of meals. You will wear a blood pressure cuff, glucose monitor, and a Fitbit for 2 days to measure your 24-hour blood pressure rhythm and the timing of ...

Researchers at the University of Kentucky are inviting you to participate in a study investigating the changes in fat tissue in response to two different medications which may increase your brown and beige fat. Brown fat, and the browning of your white fat, may protect people from obesity and reduce ...

The purpose of this research study is to investigate whether the trial product is effective and safe in reducing/managing weight in children. Winthrop-University Hospital Clinical Trials Center is seeking study participants (ages 7-11 years old), who have not started puberty to take part in this clinical research study because he/she ...

The purpose of this study is to compare cardiometabolic health between metabolically-normal and metabolically abnormal obese participants. This study will last up to 1 year. Participants will visit the research center about 6 times before randomization. The outpatient visits range from less than 1 hour to approximately 4 hours in ...

The study drug reduces CVS events and type 2 Diabetes mellitus in overweight patients

A study to evaluate the effect of long-term treatment with Belviq® (Lorcaserin HCI) on the incidence of major adverse cardiovascular events and conversion to Type 2 Diabetes Mellitus in obese and overweight subjects with cardiovascular disease or multiple cardiovascular risk factors. Half of the patients will be randomly assigned to ...