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Nephropathy Clinical Trials

A listing of Nephropathy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (100) clinical trials

A research study is evaluating an investigational medication for kidney disease due to diabetes (diabetic nephropathy). This research study may be an option if you: • Are 18 years old or older • Are male or a postmenopausal woman, or a female without childbearing potential • Have impaired kidney function ...

Phase N/A

To demonstrate the analgesic efficacy of PEMF treatment compared to sham treatment in patients with painful diabetic distal peripheral neuropathy when treatment is administered 30 minutes twice daily.

Phase N/A

Epigenetic Contribution to the Pathogenesis of Diabetic Nephropathy in Qatari Population

Diabetic nephropathy (DN) is a common vascular complication of Type 2 diabetes (T2D) that is associated with increased mortality and poor quality of life.In industrialized countries, DN ranges first among other etiologies of end-stage renal disease (ESRD).Diabetes in Qatar is a serious health issue for the Qatari population since approximately ...

Phase N/A

Alport Syndrome Treatments and Outcomes Registry

Detailed Description: ASTOR is envisioned as a permanent organization sustained by private philanthropic and public funding sources. Recruitment of participants for the registry will consist of three approaches. First, pediatric nephrologists in the United States and Canada will be invited to participate in ASTOR. Activities of participating investigators will include ...

Phase N/A

Study of High Density Lipoprotein Function in Type 1 Diabetic Patients With Nephropathy

A number of arguments suggest that the deterioration in high density lipoproteins (HDL) functioning may worsen with the development of nephropathy during type 1 diabetes (T1D). The objective of this study will be to investigate to what extent nephropathy in T1D patients in the microalbuminuria and macroalbuminuria stages, compared to ...

Phase N/A

European Alport Therapy Registry - European Initiative Towards Delaying Renal Failure in Alport Syndrome

Early diagnosis in children with Alport syndrome (AS) with isolated hematuria opens a "window of opportunity" for early intervention. Currently there are no causal therapeutic options which are proven to delay renal failure in AS. ACE-inhibition (ACEi) has been shown to reduce proteinuria in Alport patients and to delay renal ...

Phase N/A

Targeting FMO-Mediated TMAO Formation in Kidney Disease (TMAO) Study

Twelve patients with stage 3 to 4 kidney disease will receive an intervention for four weeks and a matching placebo in a crossover study design. Reduction of serum TMAO from baseline to end of intervention will be the primary endpoint.

Phase N/A

Remote Ischemic Preconditioning Living Donor Renal Transplant Protocol

All female patients of childbearing age that qualify for this study will receive a urinary pregnancy test prior to enrollment. Application of a tourniquet will occur after induction of anesthesia and intubation with minimal possibility of causing discomfort as the patient will be anesthetized. The tourniquet will be applied preferably ...

Phase N/A

Remote Ischemic Preconditioning for Renal Protection in TAVI

Severe aortic stenosis remains a major cause of morbidity and mortality of the elderly affecting approximately 3% of elderly patients with an increasing number of patients undergoing transcatheter aortic valve interventions. As part of pre-procedural planning these patients undergo CT scans and receive contrast during the procedure. These patients often ...

Phase N/A

Contrast-Induced Nephropathy After Revision of the Prophylaxis Threshold

After administration of intravascular iodinated contrast media Contrast-Induced Nephropathy (CIN), also known as Contrast-Induced Acute Kidney Injury (CIAKI), may occur. CIN/CI-AKI is associated with increased risk of dialysis and mortality. No treatment exists for CIN/CI-AKI, therefore the focus lies on prevention. Clinical practice guidelines for the prevention of CIN/CI-AKI exist ...

Phase N/A