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Nephrotic Syndrome Clinical Trials

A listing of Nephrotic Syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (100) clinical trials

The overall purpose of the study is to assess the efficacy of three different doses of BI 655064 against placebo as add-on therapy to standard of care (SOC) treatment for active lupus nephritis in order to characterize the dose-response relationship within the therapeutic range, and select the target dose for ...

Phase

This study evaluates an investigational oral tablet compared to placebo that may help manage your blood glucose levels.  

Phase

This study is to evaluate the safety of an existing diabetes drug and how it may help individuals with kidney disease. 

Phase

The aim of the study is to assess whether an investigational drug is safe and works in people with systemic lupus erthematosus (SLE). The investigational drug will be compared with a placebo. A placebo looks exactly like the investigational drug and is given the same way but contains no active ...

Phase

NEPTUNE consists of two longitudinal observational cohort studies. - One of which is following patients with biopsy proven FSGS, MCD or MN (cohort A). - The other longitudinal observational cohort study is on children who were recently diagnosed with nephrotic syndrome (cohort B).   There are no drugs or devices ...

Phase N/A

It is thought that the postnatal colonization of the gut influences later risk of allergic responses to food and impacts predisposition to immune-mediated diseases. The study characterizes the gut flora in patients with nephrotic syndrome and compares them to age matched siblings, with the aim to link specific flora with ...

Phase N/A

Genetic Causes of FSGS Nephrotic Syndrome or Kidney Failure

The investigators welcome anyone (with or without a family history) with unexplained, non syndromic FSGS, nephrotic syndrome, or proteinuria to join the study. Participation involves a saliva (or blood if it is preferable) sample and urine sample (if applicable). There is no cost to participate and the study can be ...

Phase N/A

Efficacy and Safety of Rituximab to That of Calcineurin Inhibitors in Children With Steroid Resistant Nephrotic Syndrome

The vast majority of children with idiopathic nephrotic syndrome respond well to corticosteroid treatment. However, as many as 20% experience a more complicated course with steroid resistance (SRNS). Repeated and prolonged courses of steroids in these children often result in long-term complications. The goal of treatment is to reduce the ...

Phase

The Iguratimod Effect on Lupus Nephritis (IGeLU)

This study is a 52-week, randomized, open, active-controlled trial of patients with active diffused lupus nephritis, to assess the efficacy and safety of a novel chemical synthetic agent iguratimod. The subjects will randomly receive iguratimod or cyclophosphamide followed with azathioprine, both combined with steroids.

Phase

Active Vitamin D And Reduced Dose Prednisolone for Treatment in Minimal Change Nephropathy

Traditionally MCN is treated with a high dose of prednisolone, which induces remission in 60-90% of patients. Prednisolone treatment contains numerous side effects and the current dose is empiric. Given the lack of efficacy evidence and the risk associated with the currently accepted treatment regimen there is a need to ...

Phase