Nephrotic Syndrome Clinical Trials

A listing of Nephrotic Syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 14 clinical trials
A Clinical Study to Evaluate the Potential Role of ACTH Gel in Patients With Scleritis (ATLAS)

ATLAS study is a clinical trial to evaluate the potential role of subcutaneous adrenocorticotropic hormone (ACTH) gel in the management of non-infectious scleritis. Specifically, the ATLAS Study aims to evaluate the safety, tolerability and effect of 2 different dose regimens of ACTH gel administered by subcutaneous (SC) injection in patients …

  • 68 views
  • 04 Oct, 2022
  • 3 locations
A Phase 2, Open-Label, Single-Arm, Cohort Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Sparsentan Treatment in Pediatric Subjects With Selected Proteinuric Glomerular Diseases (EPPIK)

To evaluate the safety, efficacy and tolerability of sparsentan oral suspension and assess changes in proteinuria after once-daily dosing over the 108-week treatment period.

proteinuria
kidney biopsy
total protein
corticosteroids
mammogram
  • 1 views
  • 11 Oct, 2022
  • 26 locations
UrApp for Childhood Nephrotic Syndrome Management (Incident Cohort)

Idiopathic nephrotic syndrome is one of the most common chronic kidney diseases in children. Patients suffer from frequent disease relapses and complications. Self-management is difficult for

  • 0 views
  • 04 Oct, 2022
  • 4 locations
Efficacy and Safety of Rituximab in the First Episode of Pediatric Idiopathic Nephrotic Syndrome (RTXFIRPedINS)

The main objective is to demonstrate, from the initial episode of nephrotic syndrome (NS) in children with standard prednisolone treatment, once complete remission has occurred, that the use of

  • 0 views
  • 04 Oct, 2022
  • 9 locations
A Pilot Randomized Clinical Trial of Transcutaneous Auricular Vagus Nerve Stimulation for the Treatment of Steroid Resistant Nephrotic Syndrome in Children (kidNEY-VNS)

Children with steroid resistant nephrotic syndrome (SRNS) are exposed to prolonged courses of immunosuppressant medications. Given the adverse side effect profiles and variable efficacy of these

  • 0 views
  • 22 Oct, 2022
  • 2 locations
An Open-Label, Long-term Study of GFB-887 in Patients With Glomerular Kidney Diseases

This is an open-label Phase 2 study evaluating the long term safety and tolerability of GFB-887 in patients with focal segmental glomerulosclerosis (FSGS), and treatment-resistant minimal change disease (TR-MCD)

proteinuria
segmental glomerulosclerosis
focal segmental glomerulosclerosis
glomerulosclerosis
minimal change disease
  • 0 views
  • 07 Oct, 2022
  • 17 locations
Efficacy and Safety of VB119 in Subjects With Minimal Change Disease (MCD) and Focal Segmental Glomerulosclerosis (FSGS)

Phase 2, multi-center, proof-of-concept study to evaluate the safety and efficacy of VB119 on the maintenance of remission and duration of response in adults with primary MCD or primary FSGS who previously responded to steroid therapy.

proteinuria
remission
steroid therapy
steroid treatment
corticosteroids
  • 0 views
  • 04 Oct, 2022
  • 8 locations
Tumor Necrosis Factor Inhibition in Focal Segmental Glomerulosclerosis and Treatment Resistant Minimal Change Disease

The researchers are testing adalimumab, a treatment which blocks tumor necrosis factor (TNF), to see if it changes levels of urine biomarker levels (TIMP1 and MCP1). The outcomes may help develop individualized treatment options for future patients with TNF driven Focal segmental glomerulosclerosis (FSGS) or minimal change disease (MCD).

steroid therapy
total protein
steroid treatment
biopsy tissue
angiotensin converting enzyme
  • 12 views
  • 04 Oct, 2022
  • 3 locations
Efficacy of Belimumab and Rituximab Compared to Rituximab Alone for the Treatment of Primary Membranous Nephropathy (ITN080AI) (REBOOT)

participants with PM. Background Primary membranous nephropathy (MN) is among the most common causes of nephrotic syndrome in adults. MN affects individuals of all ages

proteinuria
remission
systemic lupus erythematosus
autoimmune diseases
glomerular filtration rate
  • 340 views
  • 13 Oct, 2022
  • 11 locations
Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

Background Membranous nephropathy is associated with damage to the walls of the glomeruli, the small blood vessels in the kidneys that filter waste products from the blood. This damage causes leakage of blood proteins into the urine and is associated with low blood protein levels, high blood cholesterol values, and …

proteinuria
intravenous infusions
active treatment
edema
cyclosporine
  • 243 views
  • 21 Oct, 2022
  • 2 locations