Geographic Atrophy Clinical Trials

A listing of Geographic Atrophy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 15 clinical trials
Long-Term Analysis of DImethyl Fumarate, to Slow the Growth of Areas of Geographic Atrophy (LADIGAGA)

The primary objectives of the study are to assess the safety, tolerability and evidence of activity of 12 months oral treatment with TEFIDERA® in subjects with Geographic Atrophy associated with

retinal pigment
atrophy
geographic atrophy
  • 0 views
  • 04 Oct, 2022
A Phase 2, Double-Masked, Placebo-Controlled, Dose Range Finding Study of Danicopan (ALXN2040) in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)

This is a dose finding study designed to evaluate the efficacy, safety, and pharmacokinetics of danicopan in participants with GA secondary to AMD. The study consists of a Screening Period of up to 6 weeks, a 104-week masked Treatment Period, followed by a 30-day Follow-up after the last dose. This …

atrophy
geographic atrophy
  • 1 views
  • 15 Oct, 2022
  • 59 locations
Restoration of Central Vision With the PRIMA System in Patients With Atrophic Age-Related Macular Degeneration (PRIMAvera)

The objective of this study is to evaluate the efficacy and safety of the PRIMA System in patients with atrophic AMD. Eligible subjects will be implanted with the PRIMA Implant. The subjects will be assessed with various visual function and functional vision tests at defined timepoints throughout the clinical investigation …

vision test
corrected visual acuity
atrophy
geographic atrophy
  • 0 views
  • 21 Oct, 2022
  • 20 locations
GOLDEN STUDY: A Study to Assess Safety and Efficacy of Multiple Doses of IONIS-FB-LRx in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD)

Evaluate the effect of IONIS-FB-LRx on the rate of change of the area of geographic atrophy (GA) secondary to age-related macular degeneration (AMD) measured by fundus autofluorescence

fundus autofluorescence imaging
macular degeneration
age-related macular degeneration
mydriasis
pneumoniae
  • 1382 views
  • 04 Oct, 2022
  • 84 locations
HORIZON: A Phase II Study to Evaluate the Safety and Efficacy of Two Doses of GT005

The purpose of this clinical study is to evaluate the safety and efficacy of two doses of GT005 administered as a single subretinal injection in subjects with geographic atrophy secondary to age

  • 73 views
  • 04 Oct, 2022
  • 63 locations
A Phase 1b Multicenter, Randomized, Controlled, Single-dose Study of the Safety and Tolerability of ONL1204 Ophthalmic Solution in Patients With Geographic Atrophy (GA) Associated With Age-related Macular Degeneration (AMD

The purpose of this study is to evaluate the safety and tolerability of intravitreal injection of ONL1204 Ophthalmic Solution in patients with geographic atrophy associated with AMD

fundus autofluorescence imaging
neovascularization
geographic atrophy
detachment
ophthalmic solution
  • 5 views
  • 22 Oct, 2022
  • 4 locations
Multicenter Clinical Study of the SING-IMT in Patients With Late-stage AMD (CONCERTO)

The objective of this study is to determine the safety and effectiveness of the smaller incision, new generation (SING), implantable miniature telescope (IMT) in patients with moderate-severe central vision loss due to late-stage age-related macular degeneration (AMD).

  • 7 views
  • 04 Oct, 2022
  • 2 locations
A Multicenter, Open-Label Extension Study to Evaluate the Long-Term Safety and Tolerability of Intravitreal Injections of FHTR2163 in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration

participants with geographic atrophy (GA) secondary to age-related macular degeneration (AMD) who completed the parent study (NCT03972709/GR40973).

corrected visual acuity
atrophy
geographic atrophy
  • 63 views
  • 16 Sep, 2022
  • 49 locations
A Phase II, Multicenter, Randomized, Single-Masked, Sham-Controlled Study to Assess Safety, Tolerability, and Efficacy of Intravitreal Injections of FHTR2163 in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GALLEGO) (GALLEGO)

participants with geographic atrophy (GA) secondary to age-related macular degeneration (AMD) compared with sham control. After completing the study's last visit (Week 76), eligible participants will have the

macular degeneration
neovascularization
geographic atrophy
corrected visual acuity
age-related macular degeneration
  • 390 views
  • 15 Sep, 2022
  • 69 locations
Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration

Background Age-related macular degeneration is a common eye disease in people over 50. The "dry" form of the disease can worsen into geographic atrophy, causing

fundus autofluorescence imaging
detachment
ophthalmic solution
fundus photography
drusen
  • 549 views
  • 04 Oct, 2022
  • 1 location