Pneumococcal Disease Clinical Trials

A listing of Pneumococcal Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 95 clinical trials
Featured trial
Pneumococcal Infection

prevent coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2), with a 23-valent pneumococcal polysaccharide vaccine for the prevention of pneumococcal disease

covid-19
polysaccharide
  • 0 views
  • 18 Apr, 2022
  • 1 location
Featured trial
Pneumococcal Infection

prevent coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2), with a 23-valent pneumococcal polysaccharide vaccine for the prevention of pneumococcal disease

polysaccharide
conjugate vaccine
covid-19
pneumococcal
  • 2 views
  • 13 Jan, 2022
  • 1 location
Mass Campaigns With Fractional Dose Pneumococcal Vaccines in Sub-Saharan Africa (fPCV) (fPCV)

The aim of this study is to assess the impact of a mass campaign with a single, fractional dose of Pneumosil®, a PCV10, on VT carriage. A 20% fractional dose (1/5th) will be used as a practical formulation to prepare and administer. This study will assess whether the impact of …

Accepts healthy volunteers
  • 0 views
  • 17 Jun, 2022
  • 1 location
A Phase 3, Randomized, Double-blind, Active Comparator-controlled Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of V116 in Pneumococcal Vaccine-naïve Adults

This is a phase 3, randomized, double-blind, active comparator-controlled study of the safety, tolerability, and immunogenicity of V116 compared to PCV20 (pneumococcal 20-valent conjugate vaccine ([Prevnar 20™ / APEXXNAR™]) in pneumococcal vaccine-naïve adults. It is hypothesized that V116 is noninferior to PCV20 for the common serotypes and superior to PCV20 …

pneumococcal vaccine
Accepts healthy volunteers
conjugate vaccine
prevnar
  • 7 views
  • 24 Oct, 2022
  • 96 locations
A Phase 3 Randomized, Double-blind, Active Comparator-controlled, Lot-to-Lot Consistency Study to Evaluate the Safety, Tolerability, and Immunogenicity of V116 in Adults 18 to 49 Years of Age

This study will evaluate the safety, tolerability, and immunogenicity of a pneumococcal 21-valent conjugate vaccine (V116) in pneumococcal vaccine-naïve adults 18 to 49 years of age. The primary study hypothesis is that all 3 lots of V116 are equivalent as assessed by the serotype-specific opsonophagocytic activity (OPA) Geometric Mean Titers …

pneumococcal vaccine
conjugate vaccine
Accepts healthy volunteers
polysaccharide
  • 0 views
  • 21 Oct, 2022
  • 36 locations
  • 15 views
  • 23 Oct, 2022
  • 12 locations
A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety, Tolerability, and Immunogenicity of the Concomitant Administration of Either 23-Valent Pneumococcal Polysaccharide Vaccine or 15-Valent Pneumococcal Conjugate Vaccine With a Booster Dose of SARS-CoV-2 mRNA Vaccine in Healthy Adults 50 Years of Age or Older.

prevent coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2), with a 23-valent pneumococcal polysaccharide vaccine for the prevention of pneumococcal disease

polysaccharide
conjugate vaccine
booster
chronic illness
Accepts healthy volunteers
  • 5 views
  • 13 Oct, 2022
  • 44 locations
Evaluation of PCV Schedules in a Naive Population in Vietnam

The cost of pneumococcal conjugate vaccine use can be greatly reduced by making use of existing herd immunity to protect children against vaccine type pneumococci. The investigators will reduce the circulation of vaccine type pneumococci to low levels by PCV catch-up campaign; vaccinating all children less than 3 years of …

  • 0 views
  • 19 Jun, 2021
  • 1 location
A Controlled Human Pneumococcal Infection Model (PIM) Study (PIM)

the development of pneumococcal disease. Previously, an Experimental Human Pneumococcal Carriage (EHPC) model has been developed at the Liverpool School of Tropical Medicine (LSTM). The current study

meningitis
vaccination
Accepts healthy volunteers
antibiotics
pneumonia
  • 0 views
  • 17 Jun, 2022
  • 1 location
Sequential Versus Simultaneous Pneumococcal Vaccination in Elderly: Immunological Memory and Antibody Levels

The purpose of the present study is to compare the immunological response of pneumococcal serotype specific B-cells, the humoral immune response and safety after sequential vaccination versus simultaneous vaccination with 13-valent pneumococcal conjugate vaccine (PCV13) and 23-valent polysaccharide vaccine (PPV23) versus single vaccination with PPV23 in a prospective, randomized controlled …

pneumococcal conjugate
conjugate vaccine
vaccination
polysaccharide
  • 5 views
  • 11 Sep, 2021
  • 1 location