Healthy Volunteers Clinical Trials

A listing of Healthy Volunteers medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 911 clinical trials
Role of Nasal Dysbiosis in Parkinson Disease (SMELLPARK)

Olfactory dysfunction is frequent in Parkinson Disease (PD) and may be present years before the motor symptoms appear. The early olfactory dysfunction could result from environmental factors acting through the nasal cavity such as microbial communities. In across-sectional bicentric study, groups of 160 PD patients and 160 controls will be …

motor symptoms
Accepts healthy volunteers
  • 1 views
  • 16 May, 2022
  • 1 location
Integrated Radiographic and Metabolomics Risk Assessment in Patients With Interstitial Lung Diseases (IRM-ILD)

The purpose of this study is to find out if combining a state-of-the-art form imaging modality with metabolomics in different types of Interstitial Lung Diseases (ILD) patients compared to controls with chronic obstructive pulmonary disorder (COPD)/emphysema and healthy controls will be a better predictor of disease progression. ILD's are a …

fibrosis
emphysema
interstitial lung disease
chronic obstructive pulmonary disease
Accepts healthy volunteers
  • 44 views
  • 06 May, 2022
  • 1 location
Natural History of Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Transplant and Including Healthy Controls

Background This study follows people who have had, or will soon have, a transplant using stem cells from another person. This is known as an allogeneic hematopoietic stem cell transplant (HSCT). Graft-versus-host disease (cGVHD) can happen after HSCT. cGVHD can cause mouth problems and more serious issues. Researchers want to …

chronic graft versus host disease
bone marrow transplant
allogeneic hematopoietic stem cell transplant
Accepts healthy volunteers
  • 12 views
  • 20 Sep, 2022
  • 1 location
Novel Molecular Spectrometric Biomarkers in Blood Plasma as an Early Diagnostic Tool in HCC

Due to providing valuable clinical information while being minimally invasive, blood-based testing will most likely be a prerequisite for future large-scale screening of high-risk populations. As a variety of pathological processes, including carcinogenesis, may cause changes in both the concentration and the structure and spatial arrangement of body biomolecules, the …

encephalopathy
ascites
elastography
cancer
jaundice
  • 1 views
  • 23 Jan, 2021
  • 1 location
UCLA Perinatal Biospecimen Repository

The purpose of this investigator-initiated prospective observational cohort study is to establish the new UCLA Perinatal Biospecimen Repository (Perinatal Repository) for collection, storage, and distribution of the human data and biospecimens of the participants with perinatal pathology. The secure and shared high-quality resource of clinical data and biological specimens (Repository …

Accepts healthy volunteers
  • 79 views
  • 21 Jul, 2022
  • 1 location
Relationship Between Breast Cancer Subtypes and Immune Checkpoints

Breast cancer is the most common type of cancer in women and the second most common cause of death after lung cancer. The luminal group A, which has the highest prevalence among breast cancers; It includes Her2-negative tumors with low proliferative activity, low mitotic rate and histological grade. The prognosis …

HER2
triple negative breast cancer
ki-67
tumor cells
erbb2
  • 0 views
  • 21 Jul, 2022
  • 2 locations
Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing

Background Amyotrophic lateral sclerosis type 4 (ALS4) is an inherited motor neuron disease. People with ALS4 have a change in the amount of RNA and DNA that bind together. This binding of RNA with DNA forms units called R-loops. Researchers want to learn how R-loops are related to ALS4. To …

Accepts healthy volunteers
  • 0 views
  • 23 Jul, 2022
  • 1 location
Collection of Peripheral Blood Mononuclear Cells (PBMCs) From Healthy Subjects for the Expansion of T Cells for Adoptive Cell Therapy

Title: Collection of Peripheral Blood Mononuclear Cells (PBMCs) from Healthy People for the Expansion of T Cells for Adoptive Cell Therapy Background New therapies are being developed that use a person s own immune system to fight tumors. Some of the tumors being studied include cancers caused by viruses. Researchers …

hepatitis b
cancer
systolic blood pressure
diastolic blood pressure
Accepts healthy volunteers
  • 263 views
  • 17 Sep, 2022
  • 1 location
Collection of Blood, Body Fluid and Tissue Specimens From Healthy Donors for Use in In Vitro Research

Increased numbers of white blood cells called eosinophils can cause disease. To investigate this disease, researchers need blood, urine, sputum, stool, cerebrospinal fluid, skin and/or bone marrow samples to compare to samples from patients with this problem. Some of the samples will be used for genetic testing or future research. …

Accepts healthy volunteers
  • 55 views
  • 17 Sep, 2022
  • 1 location
Assessment of Microcirculation Alteration With Both Sublingual Microcirculation and Near-infrared Spectroscopy on ARDS

Microcirculatory alterations are frequently observed in critically ill and severe sepsis patients characterized by a decrease in capillary density and an increase in heterogeneity of perfusion. This derangements result in microcirculatory shunting and oxygen extraction deficit, and plays a major role in the pathophysiology of sepsis and multi-organ failure. Loss …

acute lung injury
assisted ventilation
mechanical ventilation
acute respiratory distress
hypoxia
  • 0 views
  • 21 Mar, 2022
  • 1 location