Healthy Volunteers Clinical Trials

A listing of Healthy Volunteers medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 168 clinical trials
Safety Tolerability and Immunogenicity of INO-4700 for MERS-CoV in Healthy Volunteers

The purpose of this Phase 2a, randomized, blinded, placebo-controlled, multi-center study is to evaluate the safety, tolerability and immunogenicity of INO-4700 administered by intradermal (ID) injection followed by electroporation (EP) using the CELLECTRA 2000 device in healthy adult volunteers for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection. This study is …

  • 0 views
  • 19 Sep, 2021
  • 4 locations
Seamless Controlled Trial To Evaluate Safety And Immunogenicity of Chikungunya Vaccine in LatinAmerica and Asia

This study has a Phase II with part A and part B and a Phase III with part C. This Adaptive seamless design will prospectively include planned modifications and incorporate both dose selection (parts A and B) and confirmation of the selected dose (part C) based on the accumulation of …

  • 39 views
  • 05 Sep, 2021
  • 8 locations
The Pharmacokinetics (PK) Safety Tolerability of SR419 in Healthy Volunteers

This is a randomized, double-blind, placebo-controlled phase I PK bridging study to evaluate the PK, safety and tolerability of SR419 in healthy subjects.

  • 0 views
  • 08 Sep, 2021
  • 1 location
Serotonergic Modulation of Cognition Emotion and Brain Activation in Healthy Volunteers

The aim of this project is: To apply a pharmacological tool of selective serotonin (5-hydroxytryptamine, 5-HT system) reuptake inhibition in healthy humans. Specifically: To investigate how sub-chronic administration of 20 mg of escitalopram affects cognitive performance ('cold' cognition) and social-emotional functioning ('hot' cognition) compared with placebo; and To investigate how …

  • 52 views
  • 19 Sep, 2021
  • 1 location
A Single and Multiple Ascending Dose Study of Niclosamide in Healthy Volunteers

A single and multiple ascending dose study of ANA001 in healthy adults to assess the safety and pharmacokinetics

  • 0 views
  • 16 Sep, 2021
  • 1 location
Dose-ranging Study: Safety Tolerability and Immunogenicity of INO-4500 in Healthy Volunteers in Ghana

electroporation (EP) using CELLECTRA 2000 device in healthy volunteers in Ghana.

  • 0 views
  • 19 Sep, 2021
  • 1 location
A Study to Assess an ATX Inhibitor (IOA-289) in Healthy Volunteers

The purpose of Part 1 of this First-in-Human trial is to evaluate the safety and tolerability after single ascending oral doses of IOA-289 given to healthy male subjects, compared to placebo. After the oral dose administrations, the amount of IOA-289 present in serum will be determined for pharmacokinetic characterisation. Also …

  • 0 views
  • 06 Sep, 2021
  • 1 location
A Study Evaluating Relative Bioavailability of an Oral Suspension of Abrocitinib and Effect of an Acid Reducing Agent on the Bioavailability of Abrocitinib and Assessing the Taste of Abrocitinib Oral Formulations.

This study consists of 2 parts: Part A is to estimate the relative bioavailability of a single 200 mg dose of abrocitinib oral suspension (Test formulation) compared to the commercial abrocitinib tablet (200 mg) (Reference formulation). The effect of an acid-reducing agent on the pharmacokinetics of abrocitinib and its metabolites …

  • 0 views
  • 19 Sep, 2021
  • 1 location
Study to Assess Bioequivalence and Adhesion Properties Between Two Granisetron Transdermal Patches.

The study is designed to evaluate the BE and adhesion properties of granisetron transdermal patches manufactured at 2 different sites. The study has been designed in accordance with the FDA Guidance for Industry. Bioequivalence will be based on the Cmax and AUC to determine the peak and total drug exposure, …

  • 0 views
  • 09 Sep, 2021
  • 1 location
A Study of TAK-105 in Healthy Adults

It is hoped that in the future, TAK-105 will be used to help treat people with nausea and vomiting. The main aims of this study are as follows: To check for side effects from TAK-105 in healthy adults. To learn how much TAK-105 they can receive without getting side effects …

  • 6 views
  • 10 Sep, 2021
  • 2 locations