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Musculoskeletal Diseases Clinical Trials

A listing of Musculoskeletal Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (13) clinical trials

Multicenter, randomized, double-blind, parallel-group, placebo-controlled, fixed-dosage, Phase 2a study comparing 3 dosages of LY3154207  

Phase

AMX0035 is a combination therapy designed to reduce neuronal death through blockade of key cellular death pathways originating in the mitochondria and endoplasmic reticulum (ER). This clinical trial is designed to demonstrate that treatment is safe, tolerable, and able to slow decline in function as measured by the ALSFRS-R. The ...

Phase

The purpose of this study is to assess the effect of CK-2127107 versus placebo on respiratory function and other measures of skeletal muscle function in patients with ALS.

Phase

This is a multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of GZ/SAR402671 in patients with early-stage Parkinson’s disease carrying a GBA mutation or other prespecified variant. The total study duration per subject in Part 2 will be approximately 168 weeks that will consist of 6.5 weeks ...

Phase

This study will assess the effectiveness of pimavanserin when given along with a selective serotonin reuptake inhibitor/selective norepinephrine reuptake inhibitor (SSRI/SNRI) for depression in adults with Parkinson’s disease.

Phase

A study to evaluate the safety and tolerability of SEP363856 in subjects with Parkinson's Disease Psychosis.  

Phase

This is a multicenter, multiple dose study to examine the effect of H.P. Acthar® (Acthar) on functional decline in adult subjects with amyotrophic lateral sclerosis (ALS).

Phase

The study will be conducted on an out-patient basis. Each patient will have 6 visits to the clinic: a screening visit, a randomization visit, 3 follow up visits, and 1 end of study visit. Patient randomization will be stratified based upon the baseline weekly complete spontaneous bowel movement rate (CSBM) ...

Phase