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Therapeutic Areas: | Musculoskeletal | Rheumatology
Musculoskeletal Diseases Clinical Trials
A listing of Musculoskeletal Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found (104) clinical trials
Cognite Trial – A Phase III Safety and Efficacy Study of ALZT-OP1 in Individuals with Evidence of Early Alzheimer’s Disease
This Phase III study is designed as a randomized, double-blinded, placebo-controlled study for subjects with evidence of early AD. The study will evaluate safety and tolerability, efficacy as measured by CDR-SB, and will determine if the combination therapy ALZT-OP1 will slow down, arrests, or reverse cognitive and functional decline in ...
A Randomized, Double-Blind, Placebo-Controlled, 52-Week Phase II Study to Evaluate the Efficacy of Intravenous RO7046015 (PRX002) in Participants With Early Parkinson's Disease With a 52-Week Blinded Extension
This multicenter, randomized, double-blind, placebo-controlled, Phase 2 study will evaluate the efficacy of intravenous RO7046015 versus placebo over 52 weeks in participants with early Parkinson's Disease (PD) who are untreated or treated with monoamine oxidase B (MAO-B) inhibitors since baseline. The study will consist of 2 parts: a 52-week, double-blind, ...
Evaluation of the Safety, Tolerability, Efficacy and Activity of AMX0035, a Fixed Combination of Phenylbutyrate (PB) and Tauroursodeoxycholic Acid (TUDCA), for the Treatment of ALS
AMX0035 is a combination therapy designed to reduce neuronal death through blockade of key cellular death pathways originating in the mitochondria and endoplasmic reticulum (ER). This clinical trial is designed to demonstrate that treatment is safe, tolerable, and able to slow decline in function as measured by the ALSFRS-R. The ...
A Phase 2, Multi-Center, Double-Blind, Randomized, Dose-Ranging, Placebo-Controlled Study to Evaluate the Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS)
The purpose of this study is to assess the effect of CK-2127107 versus placebo on respiratory function and other measures of skeletal muscle function in patients with ALS.
A Washington University metabolism research study seeks participants.
The purpose of this research study is to determine the effect of dietary supplements on muscle protein metabolism. There are 2 to 3 study visits. Two of the visits will be overnight stays in the research unit that will last approximately 24 hours. There will be a medical screening, body ...
ALS (Amyotrophic Lateral Sclerosis)
Is your life affected by Lou Gehrig’s disease (ALS?) Wake Research Associates is enrolling volunteers with Amyotrophic Lateral Sclerosis (ALS) in a study testing the safety and tolerability of an investigational medication.
A Washington University research study seeks participants for an online survey.
The purpose of this project is to develop a questionnaire of self-reported navigation abilities. There are no study visits to Washington University. Participation will take about 10 minutes. Participants will complete a survey online at home and will be entered to win a $50.00 gift card.
A Phase III, Randomized, Double-blind, Placebo-controlled Study of Subcutaneous Secukinumab in Autoinjectors, to Demonstrate Efficacy at 24 Weeks and Long Term Safety and Efficacy up to 3.5 Years in Subjects With Active Psoriatic Arthritis
The purpose of this study is to provide 24 - 52 week efficacy, safety and tolerability data, as well as up to 3.5-year efficacy, safety and tolerability data in subjects with active Psoriatic Arthritis despite current or previous nonsteroidal anti-inflammatory drug (NSAID), disease-modifying antirheumatic drug (DMARD) therapy and/or previous anti-tumor ...
Gout & Heart Disease
Local study doctors are looking for people with gout and heart disease to participate in a clinical research study.
Osteoarthritis or Rheumatoid Arthritis
We are seeking patients 18 years of age or older with a history of Osteoarthritis (OA) or Rheumatoid arthritis (RA) and have Cardiovascular disease or risk factors for developing cardiovascular disease.
