Musculoskeletal Diseases Clinical Trials

A listing of Musculoskeletal Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 141 clinical trials
A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform

Post-market prospective, multi-center longitudinal study to determine if mobile application-guided education and exercise paired with accurate and sensitive activity monitoring, captured from consumer wearables, can provide a viable (and potentially improved) alternative to current standard of care physical therapy for hip and knee arthroplasty.

hip arthroplasty
total knee replacement
partial knee replacement
  • 12 Sep, 2021
  • 34 locations
Natural History and Development of Spondyloarthritis

Background Spondyloarthritis (SpA) is a group of bone and joint disorders that may cause back and joint pain and stiffness. In some cases, SpA can lead to abnormal bone growth affecting the joints and spine. Some patients have SpA without ever developing these growths, while others develop them after only …

  • 19 Sep, 2021
  • 1 location
Genicular Artery Embolization to Reduce Pain Associated With Unilateral Mild to Moderate Osteoarthritis

The goal of this study is to perform a feasibility study to show the effectiveness of the genicular artery embolization procedure in reducing bilateral or unilateral osteoarthritic knee pain at 12 months as measured by WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) score, Knee Injury and Osteoarthritis Outcome (KOOS) …

  • 19 Sep, 2021
  • 1 location
Investigating Racial Differences in Diet Benefits for Knee Osteoarthritis

Knee osteoarthritis (OA) is the most prevalent form of arthritis and race is a risk factor for poor outcomes. African-Americans (AAs) report greater OA-related disability and pain severity compared to their Non-Hispanic White (NHW) counterparts. These disparities are reinforced through social and biological mechanisms, ultimately resulting in dramatic racial disparities …

  • 19 Sep, 2021
  • 1 location
Clinical Study of Cord Blood Mononuclear Cells (UCB-MNCs) in the Treatment of Knee Osteoarthritis

Umbilical cord blood mononuclear cells contain hematopoietic stem cells (HSC), mesenchymal stem cells (MSC), endothelial progenitor cells and other pluripotent stem cells, as well as immature immune cells, which can differentiate into chondrocytes, hematopoietic, epithelial, endothelial and nerve cells. It gives the ability to promote wound healing and vascular microcirculation …

intra-articular injection
  • 12 Sep, 2021
  • 1 location
Needling Techniques for Knee Osteoarthritis

The purpose of this open-label, twenty-four weeks-long clinical study is to investigate the efficacy of acupuncture for Knee Osteoarthritis (KOA) as adjunctive therapy to conventional treatment in comparison to conventional therapy alone and assessment of its eventual prolonged efficacy after nine weeks without treatment. Long term effects of acupuncture on …

  • 20 Sep, 2021
  • 1 location
Anterior Advantage With KINCISE

This is a post-market prospective, 1:1 randomized, multicenter non-inferiority study to compare the femoral broaching time for THA with the Anterior Advantage approach with KINCISE vs. without KINCISE. Follow-up will continue through 24 weeks post-op.

hip arthroplasty
joint reconstruction
hip replacement
  • 15 Sep, 2021
  • 8 locations
Post Market Clinical Follow-up (PMCF) Study of the A.L.P.S. Proximal Humerus Plating System

This study is a multicenter, prospective, non-randomized, non-controlled post-market clinical follow-up study. The primary objective of this study is to confirm the safety and performance of the A.L.P.S. Proximal Humerus Plating System applied in proximal humerus fracture treatment.

conservative management
conservative treatment
humeral fracture
fracture treatment
conservative therapy
  • 19 Sep, 2021
  • 2 locations
Actis Total Hip System 2 Year Follow-up

Two-year (2 year) information regarding the performance of the commercially available Actis Total Hip System in order to obtain and evaluate the clinical outcomes on a series of cementless primary total hip arthroplasty (THA) and hemi-hip arthroplasty procedures using clinical, radiographic and device and procedure related adverse event assessments.

rheumatoid arthritis
dislocation of the hip
avascular necrosis
internal fixation
hip replacement
  • 16 Sep, 2021
  • 10 locations
Blood-Flow Restriction Exercise Following a Knee Replacement

This study will determine the safety and efficacy of using blood-flow restriction exercise enhancement (B-FREE) to overcome persistent quadriceps muscle weakness that occurs following a total knee replacement (TKR).

total knee replacement
knee injury
  • 06 Sep, 2021
  • 1 location