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Musculoskeletal Diseases Clinical Trials

A listing of Musculoskeletal Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (272) clinical trials

Dr. Kevin Black will look at the safety and effectiveness of an investigational drug compared to placebo (inactive substance) in the treatment of Parkinson’s disease with psychosis. Participation in this study may last up to 12 weeks. There will be a screening visit lasting about 3 hours and up to ...

Phase

Primary Objective: To compare the pharmacokinetics (PK) of single and multiple doses of IPX203 with Immediate release carbidopa-levodopa (IR CD-LD) in subjects with advanced Parkinson's disease (PD). Secondary Objectives: To compare the pharmacodynamics of single and multiple doses of IPX203 with IR CD-LD. To compare the efficacy of IPX203 with ...

Phase

The purpose of the study is to determine how quickly a protein called Alpha-synuclein (a-syn) is cleared from the body in participants with Parkinson’s disease. A-syn is a major component of Parkinson’s disease. There are up to 7 study visits. Participation includes neurological/physical exam, vitals, blood draws and lumbar puncture ...

Phase N/A

The study will involve an eighteen-week, double-blind, placebo-controlled parallel designed comparison between add-on topiramate and add-on placebo to stable treatment with amatadine in the treatment of PD patients who continue to have dyskinesia on amantadine.

Phase

The purpose of this study is to assess the effect of CK-2127107 versus placebo on respiratory function and other measures of skeletal muscle function in patients with ALS.

Phase

Patients with rheumatoid arthritis can develop unpredictable worsening of their disease (flare) that is extraordinarily painful and limits ability to function. Flares are often preceded by early warnings of fatigue and flu-like symptoms. It is not known how long these early warning symptoms last or what causes them. It is ...

Phase N/A

Is your life affected by Lou Gehrig’s disease (ALS?) Wake Research Associates is enrolling volunteers with Amyotrophic Lateral Sclerosis (ALS) in a study testing the safety and tolerability of an investigational medication.  

Phase

6.1 PRIMARY The primary objective of the study is to evaluate treatment satisfaction as the primary Patient- Reported Outcome (PRO) in patients with relapsing forms of MS (RMS) treated with LEMTRADA in a real life setting using the Treatment Satisfaction Questionnaire for Medication (TSQM) version 1.4. 6.2 SECONDARY The secondary ...

Phase N/A

The purpose of this prospective parallel-cohort study in patients with relapsing forms of MS, either newly treated with fingolimod or receiving another disease-modifying therapy, is to further monitor the overall safety profile of fingolimod under conditions of routine medical practice and to explore the incidence of selected safety related outcomes. ...

Phase

Multicenter, randomized, double-blind, parallel-group, placebo-controlled, fixed-dosage, Phase 2a study comparing 3 dosages of LY3154207  

Phase