Pentalogy of Cantrell Clinical Trials

A listing of Pentalogy of Cantrell medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 44 clinical trials
Featured trial
A Research Study for Pentalogy of Cantrell

This study will collect blood, urine, and other tissue samples from patients with Pentalogy of Cantrell (POC) and other inherited diseases that may involve mutations in non-muscle myosin II-B

nervous system disorders
nervous system disease
congenital disorders
  • 19 views
  • 22 Dec, 2020
  • 1 location
Trifluridine/Tipiracil (TAS-102) With or Without Thalidomide for the Treatment of Metastatic Colorectal Cancer

Thalidomide has both anti-angiogenesis and antiemetic effects, and its combined use with TAS-102 may reduce the gastrointestinal reactions associated with TAS-102, while enhancing antitumor

  • 0 views
  • 15 Mar, 2022
Safety of Cetuximab and Trifluridin Tipiracil as the Third-line Therapy in the RASwt mCRC

This was a single-arm, prospective study to investigate the safety of cetuximab in combination with trifluridin tipiracil (TAS-102) in the third-line treatment of Chinese patients with RAS wild

  • 0 views
  • 07 Oct, 2022
  • 1 location
Assessing a Regorafenib-irinotecan Combination Versus Regorafenib Alone in Metastatic Colorectal Cancer Patients (NEXT-REGIRI)

Patients with metastatic colorectal cancer (mCRC) who have received all approved standard treatments (except Regorafenib and TAS 102) no longer have treatment options available while maintaining

  • 25 views
  • 03 Feb, 2022
  • 11 locations
TAS-117 in Patients With Advanced Solid Tumors Harboring Germline PTEN Mutations

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and antitumor activity of TAS-117 in patients with advanced or metastatic solid tumors

  • 0 views
  • 01 May, 2022
  • 7 locations
A Phase 2 Study of TAS-120 in Metastatic Breast Cancers Harboring Fibroblast Growth Factor Receptor (FGFR) Amplifications

The purpose of the trial is to evaluate a patient's response to a Fibroblast Growth Factor Receptor (FGFR) inhibitor, futibatinib (TAS-120), used either alone or in combination with the hormonal

metastasis
progesterone receptor
neutrophil count
platelet count
measurable disease
  • 76 views
  • 20 Oct, 2022
  • 29 locations
The Effect of Single vs Multiple Prophylactic Antibiotic Doses on PJI Following Primary THA in Patients With Osteoarthritis: A Cross-over, Cluster Randomized Controlled, Non-inferiority Trial Based on National Quality Databases. ProHipQ-OA (ProHipQ-OA)

inclusion criteria will be involved: Based on national quality databases, two-year cohorts of approximately 20,000 primary THAs conducted at all public and private orthopedic departments in Denmark, this

hip arthroplasty
osteoarthritis
antibiotics
joint arthroplasty
  • 0 views
  • 22 Oct, 2022
  • 17 locations
A Phase 3, Randomized, Open-label Study of Relatlimab-nivolumab Fixed-dose Combination Versus Regorafenib or Trifluridine + Tipiracil (TAS-102) for Participants With Later-lines of Metastatic Colorectal Cancer (RELATIVITY-123)

The purpose of this study is to evaluate relatlimab in combination with nivolumab, administered as a fixed-dose combination (nivolumab-relatlimab FDC, also referred to as BMS-986213) for the treatment of non-microsatellite instability high (MSI-H)/deficient mismatch repair (dMMR) metastatic colorectal cancer (mCRC) participants who failed at least 1 but no more than …

  • 0 views
  • 25 Oct, 2022
  • 20 locations
The Effect of Single vs Multiple Prophylactic Antibiotic Doses on PJI Following Primary THA in Patients With a Fracture: A Cross-over, Cluster Randomized Controlled, Non-inferiority Trial Based on National Quality Databases: ProHipQ-F (ProHipQ-F)

THAs due to a fracture or sequelae to a fracture, conducted at all public and private orthopedic departments in Denmark, this includes 36 sites corresponding to a total of 39 departments.

antibiotics
  • 0 views
  • 28 Oct, 2022
  • 17 locations
Tailored Axillary Surgery With or Without Axillary Lymph Node Dissection Followed by Radiotherapy in Patients With Clinically Node-positive Breast Cancer (TAXIS) (TAXIS)

RATIONALE: The use of tailored axillary dissection as a tailored procedure will avoid surgical overtreatment by selectively removing the lymph nodes that are affected by the cancer, thereby sparing many women the unnecessary complications of a radical surgery, providing a better quality of life while keeping the same efficacy. PURPOSE: …

  • 12 views
  • 12 Feb, 2022
  • 62 locations