Allogeneic Hematopoietic Stem Cell Transplant Clinical Trials

A listing of Allogeneic Hematopoietic Stem Cell Transplant medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 36 clinical trials
A Multicenter ,Prospective, Randomized Clinical Trial of Blinatumomab As a Bridge to Allogeneic Hematopoietic Stem Cell Transplantation in High Risk Precursor B-cell Acute Lymphoblastic Leukemia

To explore the efficacy and safty of Blinatumomab as a bridge to Allogeneic Hematopoietic Stem Cell Transplantation in High Risk Precursor B-cell Acute Lymphoblastic Leukemia

  • 0 views
  • 16 Oct, 2022
  • 1 location
Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) Antagonists

Background Chronic granulomatous disease (CGD) affects the immune system. People with CGD are more likely to get infections. Drugs can help control infections, but these treatments can cause side effects including kidney failure and deafness. Stem cell transplants can cure CGD, but these don t always work. Objective To find …

  • 0 views
  • 04 Oct, 2022
  • 1 location
Safety and Effectiveness of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood

Quizartinib is an experimental drug. It is not approved for regular use. It can only be used in medical research. Children or young adults with a certain kind of blood cancer (FLT3-ITD AML) might be able to join this study if it has come back after remission or is not …

induction chemotherapy
remission
consolidation therapy
cancer
flt3 internal tandem duplication
  • 61 views
  • 07 Oct, 2022
  • 38 locations
Allogeneic Hematopoietic Stem Cell Transplant for Patients With Mutations in GATA2 or the MonoMAC Syndrome

Background GATA2 deficiency is a disease caused by mutations in the GATA2 gene. It can cause different types of leukemia and other diseases. Researchers want to see if a stem cell transplant can be used to treat this condition. A stem cell transplant will give stem cells from a matching …

conjugated bilirubin
direct bilirubin
bone marrow procedure
therapeutic agents
cancer
  • 26 views
  • 24 Oct, 2022
  • 1 location
A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome

Background Allogeneic hematopoietic stem cell transplant involves taking blood stem cells from a donor and giving them to a recipient. The transplants are used to

total body irradiation
fludarabine
cyclophosphamide
busulfan
x-rays
  • 0 views
  • 21 Oct, 2022
  • 1 location
ONC 201 Maintenance Therapy in Acute Myeloid Leukemia and Myelodysplastic Syndrome After Stem Cell Transplant

This is a single-center pilot study of 20 patients with AML/MDS. Eligible patients will be enrolled following an informed consent between 6-20 weeks after allogeneic hematopoietic stem cell

bone marrow procedure
granulocyte colony stimulating factor
myeloid leukemia
remission
growth factor
  • 18 views
  • 04 Oct, 2022
  • 1 location
Cemiplimab in AlloSCT/SOT Recipients With CSCC

In this research study, Cemiplimab is being evaluated as a treatment for advanced cutaneous squamous cell carcinoma in participants who have previously received an allogeneic hematopoietic stem

sirolimus
cemiplimab
serum follicle stimulating hormone
acute gvhd
prednisone
  • 0 views
  • 04 Oct, 2022
Human Lysozyme Goat Milk for the Prevention of Graft Versus Host Disease in Patients With Blood Cancer Undergoing a Donor Stem Cell Transplant

This phase I trial studies the side effects of human lysozyme goat milk in preventing graft versus host disease in patients with blood cancer undergoing a donor stem cell transplant. Sometimes the transplanted cells from a donor can cause an immune response against the body's own normal cells (call graft …

graft versus host disease
sirolimus
total body irradiation
cyclophosphamide
cancer
  • 0 views
  • 04 Oct, 2022
  • 1 location
Pilot Trial of Pravastatin as a Novel Prophylactic Medicine to Reduce Endothelial Injury in Pediatric Patients With Elevated Body Mass Index

injury after BMT. The investigator hypothesizes that prophylactic pravastatin in pediatric allogeneic hematopoietic stem cell transplant recipients with elevated BMI is safe and feasible.

  • 0 views
  • 22 Oct, 2022
  • 1 location
Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders

, ,myelodysplastic syndromes, myeloproliferative neoplasms, or related blood disorders who are going to receive chemotherapy or another treatment to prepare the body for an allogeneic hematopoietic stem cell

leukemia
myeloid leukemia
myelomonocytic leukemia
chronic myeloid leukemia
transplant conditioning
  • 0 views
  • 07 Oct, 2022
  • 7 locations