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Multiple Sclerosis Clinical Trials

A listing of Multiple Sclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (258) clinical trials

The Swedish BioFINDER 2 Study

GENERAL AIMS: Develop methods for early and accurate diagnosis of different dementia disorders. This is important not only for the clinical diagnostic work-up, but also for selection of patients to clinical trials. Because dementia is very common among the elderly, but often misdiagnosed, we need to develop minimally invasive, reliable ...

Phase N/A

Exploring the Effectiveness of Sensor-based Balance Training on Patient Outcome Measures

Individuals suffering from certain disorders/diseases including diabetes, arthritis, cancer, osteoarthritis, stroke, Parkinson's disease, cognitive impairment or brain Injury are more likely to experience a fall or a fall-related injury than healthy individuals during to impaired postural stability or diminished joint perception. Under certain circumstance they may also experience pain, depression, ...

Phase N/A

Improving Dynamic Balance and Gait Adaptability Using Treadmill Training

Balance and gait problems in subjects with neurological disease lead to reduced mobility, loss of independence and frequent falls. Treadmill training is a widely used form of treatment and it has been used in subjects with neurological disease to ameliorate walking and balance deficits. The Virtual Reality Treadmill as a ...

Phase N/A

Adderall XR and Cognitive Impairment in MS

It is now known that Multiple Sclerosis (MS) can cause cognitive impairment (CI), estimated to occur in 40-65% of MS patients. The most frequently observed impairments in the MS population are in processing speed (PS), as well memory (working and episodic), verbal fluency, executive function and selective attention can also ...


App Based Dexterity Training in Multiple Sclerosis

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system and the most common cause of non-traumatic disability in young adults (Kamm et al. 2014; Vanbellingen & Kamm, 2016). It is a heterogeneous disease, which is associated with long-term disability, leading to reduced quality of life (QoL). ...


Treatment of Multiple Sclerosis and Neuromyelitis Optica With Regulatory Dendritic Cell: Clinical Trial Phase 1 B

First in human study to assess the tolerability and safety profile of treatment with dendritic cell in patients with multiple sclerosis or neuromyelitis optica.


Biological Activity and Safety of Low Dose IL2 in Relapsing Remitting Multiple Sclerosis

In MS-IL2, 30 RRMS patients will be treated in a randomized, double-blind, placebo controlled clinical trial. IL2 will be administered first as an induction course of IL-2 or placebo each day for 5 days, followed by a maintenance course at the same dose or placebo every two weeks over 6 ...


Behavior and Activity Monitoring in MS

Interventions to increase physical activity through aerobic exercise are some of the only known treatment options to improve domains of cognition such as executive function. While increased physical activity is associated with preserved cortical functioning during exogenous executive functioning tasks in older adults, little is known about the relationship between ...

Phase N/A

Adrenocorticotropic Hormone (ACTH) Effects on Myelination in Subjects With MS

This pilot study proposal is designed to perform a chronological measurement of MWF in new contrast-enhancing lesions in subjects treated with ACTH during an acute exacerbation of MS. The initial course of ACTH (H.P. Acthar) will be administered as recommended in the package insert, a subcutaneous daily dose of 80-120mg ...


The Effect of a Gluten Free Diet on the Permeability of the Blood Brain Barrier in Patients With CIS

Background Disruption of the blood brain barrier (BBB) is believed to play a critical role in the pathogenesis of multiple sclerosis (MS). Cramer et al. (2014) found increased BBB permeability in MS patients compared to healthy controls (HC) with values being higher in cases with recent relapses (1). Furthermore, BBB ...

Phase N/A