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Multiple Sclerosis Clinical Trials

A listing of Multiple Sclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (407) clinical trials

Swiss Multiple Sclerosis Cohort-Study

The key aims of the Swiss Multiple Sclerosis Cohort-Study (SMSC) are To maintain a long-term cohort (>10 years) representative of the MS population currently living in Switzerland. This requires effective measures to limit drop-outs and the continuous recruitment of MS patients and To conduct a systematic follow-up with standardized, high ...

Phase N/A

Biological Activity and Safety of Low Dose IL2 in Relapsing Remitting Multiple Sclerosis

In MS-IL2, 30 RRMS patients will be treated in a randomized, double-blind, placebo controlled clinical trial. IL2 will be administered first as an induction course of IL-2 or placebo each day for 5 days, followed by a maintenance course at the same dose or placebo every two weeks over 6 ...


Behavior and Activity Monitoring in MS

Interventions to increase physical activity through aerobic exercise are some of the only known treatment options to improve domains of cognition such as executive function. While increased physical activity is associated with preserved cortical functioning during exogenous executive functioning tasks in older adults, little is known about the relationship between ...

Phase N/A

PREG-MS: New England MS Pregnancy Registry

The purpose of the study is to develop a detailed pregnancy registry of patients with Multiple Sclerosis in the New England states. Women with a diagnosis of MS that are either pregnant or actively planning to become pregnant are eligible to participate. The study will solely take place through phone ...

Phase N/A

Effects of Fingolimod on Heart Rhythm and Heart Rate Variability in Patients With Multiple Sclerosis

Fingolimod (Gilenya; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA) is a novel oral disease-modifying therapy that acts as a sphingosine-1-phosphate (S1P) receptor agonist and reduces the recirculation of lymphocytes to blood and peripheral tissues, including inflammatory lesions. A critical part of fingolimod therapy still remains in the screening and initiation ...

Phase N/A

Evaluation of the First Second and New Drug-Eluting Stents in Routine Clinical Practice

Consecutive patients receiving New DES without a mixture of other DES

Phase N/A

Adrenocorticotropic Hormone (ACTH) Effects on Myelination in Subjects With MS

This pilot study proposal is designed to perform a chronological measurement of MWF in new contrast-enhancing lesions in subjects treated with ACTH during an acute exacerbation of MS. The initial course of ACTH (H.P. Acthar) will be administered as recommended in the package insert, a subcutaneous daily dose of 80-120mg ...


Prospective Investigation of Multiple Sclerosis in the Three Rivers Region

Research Activities: Initial Questionnaire, Questionnaire for Self-Reported Outcomes, Biological Sample Collection (Blood, Stool, Urine, Cerebrospinal fluid), Genetic Analysis, Standard Quantitative Assessment of Function, Cognitive Assessment, Neuroimaging, Biometric Sensors, and Social Network Questionnaire.

Phase N/A

Multiple Sclerosis: The Role of Mitochondrial Dysfunction in IR Resistance

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) and is one of the most common neurological diseases, often leading to disability of the patients. The MS pathogenesis includes vascular and inflammatory components, however recently also the role of mitochondrial dysfunction being a hot ...

Phase N/A

Combined Use of Multiple Biomarkers With Stress Testing to Detect Coronary Artery Disease

The COMBAT-CAD Study is an observational study with the aim to improve the diagnostic accuracy by a combination of stress testing with sensitive and specific biomarkers in detecting coronary artery disease or its progress. The main subjects are all patients with CAD or suspicion of CAD sent to the University ...

Phase N/A