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Multiple Sclerosis Clinical Trials

A listing of Multiple Sclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (411) clinical trials

The goal of this study is to learn more about Magnetic Resonance Imaging (MRI) and cognitive function over a 12 month period in people who have switched DMTs. In addition to your regular clinical care, you will be asked to answer questions about your health and complete the Single Digit ...

Phase N/A

The investigators are measuring the effectiveness of Ocrevus™ in helping patients with hand or arm weakness, especially if posed by a more advanced MS patient than those included in the clinical trials.

Phase N/A

The purpose of the study is to see how safe it is and how well you tolerate changing the MS medicine you are taking currently for your MS to siponimod (an investigational drug for MS). The results of this study will help doctors decide if and when to switch patients ...

Phase

Primary Objective: To estimate the annualized relapse rate (ARR) over a 24-month period in patients with RMS who are treated with cladribine tablets in a real-world setting and after suboptimal response to any oral DMD approved in the US for RMS Secondary Objectives: To assess PROs and treatment adherence during ...

Phase N/A

Primary Objective: To estimate the annualized relapse rate (ARR) over a 24-month period in patients with RMS who are treated with cladribine tablets in a real-world setting and after suboptimal response to any injectable DMD approved in the US for RMS Secondary Objectives: To assess PROs and treatment adherence during ...

Phase N/A

Secondary Objectives All-cause mortality, VT or VF alone, risk of cardiac death, and sudden cardiac death for the total cohort, as well as by sex and by the implanted device type. Compare the predicted incidence of sudden death using the Seattle Proportional Risk score to the observed incidence in this ...

Phase N/A

Primary To assess the efficacy of ravulizumab compared with placebo in the treatment of gMG based on the improvement in the Myasthenia Gravis-Activities of Daily Living (MG-ADL) profile. Secondary To assess the efficacy of ravulizumab compared with placebo in the treatment of gMG based on the improvement in the Quantitative ...

Phase

FDA-approved multiple sclerosis (MS) disease-modifying therapies (DMTs) target the relapsing phase of MS but have minimal impact once the progressive phase has begun. It is unclear if, in the relapsing phase, there is an advantage of early aggressive therapy with respect to preventing long-term disability. The infectious risks and other ...

Phase N/A

The primary objective of this study is to evaluate the efficacy of natalizumab extended interval dosing (EID) in subjects who have previously been treated with natalizumab standard interval dosing (SID) for at least 12 months, in relation to continued SID treatment. The secondary objectives are to evaluate additional clinical and ...

Phase

To assess early phase safety and tolerability of converting patients from approved oral and injectable RMS DMTs to siponimod. The results of this study will guide clinically relevant decisions related to the transition from frequently used RMS DMTs to siponimod and provide clinically relevant data on safety and tolerability for ...

Phase