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Multiple Sclerosis Clinical Trials

A listing of Multiple Sclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (411) clinical trials

Winthrop University Hospital is conducting a study for people with Primary Progressive MS and whom are willing to take an investigational medication intravenously. The purpose of this study is to determine the effectiveness and safety of an investigational medication for the treatment of Primary Progressive MS. Patient Inclusion Criteria: To ...

Phase

Are you living with Multiple Sclerosis? Have you experienced a worsening of your MS symptoms or the onset of new symptoms in the last two years? If so, you may qualify for a research study. NeuroTrials Research is conducting a 96 week, non-placebo, comparative trial to determine whether an investigational ...

Phase

Protocol # MNK14274069 This is a multicenter, multiple dose study to estimate the response rate, and examine the safety of, Acthar in subjects with RRMS who have not responded to high dose intravenous methylprednisolone (IVMP), oral prednisone, or oral methylprednisolone. Approximately 66 subjects will be randomized.

Phase

This study will assess the safety, tolerability, and efficacy of suvorexant in multiple sclerosis patients. Enrolled subjects will receive 2 weeks of treatment during treatment period 1 with either suvorexant or matching placebo (1:1). After treatment period 1, subjects will undergo a washout period of 1 week then 2 weeks ...

Phase

A clinical research study called 'POINT' will evaluate if adding an oral study drug to Tecfidera® can have an effect on multiple sclerosis (MS) disease activity. In this study, patients with active relapsing MS will receive add-on therapy with ponesimod (a sphingosine 1-phosphate [S1P] receptor modulator) or placebo on top ...

Phase

To evaluate the effects of BIIB033 versus placebo on disability improvement over 72 weeks and to evaluate the effects of BIIB033 versus placebo on additional measures of disability improvement.

Phase

This is a prospective, multicenter, open-label, single-arm, phase 3b study which evaluates effectiveness and safety of ocrelizumab in participants with early stage RRMS. The study will consist of an open-label treatment period of 192 weeks and follow-up period of at least 48 weeks.

Phase

This is a phase 3, randomized, multi-center, double-blinded, active-controlled study that is primarily designed to assess the Annualized Relapse Rate (ARR) and safety/tolerability of ublituximab/oral placebo (TG-1101; UTX) as compared to teriflunomide/ IV placebo in subjects with relapsing MS.

Phase

The study objective is to determine if the use of two or more arterial grafts in coronary artery bypass surgery (CABG) compared to a single arterial graft is associated with  improved survival. There is no "experimental" procedures being tested in this study. Cardiac surgeons use both arterial and vein grafts ...

Phase N/A

The primary purpose of this study is to demonstrate pharmacokinetic bioequivalence of ofatumumab injected by Pre-filled Syringe (PFS) versus Auto-Injector (AI) devices and thereby establish a bridge between the ongoing Phase 3 program and the to-be-marketed drug-device combinations.

Phase