Multiple Sclerosis Clinical Trials

A listing of Multiple Sclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 44 clinical trials
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A single-arm, prospective, multicentre, open-label study to evaluate ofatumumab treatment effectiveness and patient-reported outcomes in patients with relapsing multiple sclerosis transitioning from dimethyl fumarate or fingolimod therapy

This study will look to see if ofatumumab works and is safe in adults with relapsing multiple sclerosis (MS) who are switching from their current oral medicines (dimethyl fumarate or fingolimod

MRI
relapsing multiple sclerosis
disease or disorder
multiple sclerosis
fingolimod
  • 0 views
  • 17 May, 2021
  • 1 location
featured
A PHASE IIIB MULTICENTER, RANDOMIZED, DOUBLE-BLIND, CONTROLLED STUDY TO EVALUATE THE EFFICACY, SAFETY AND PHARMACOKINETICS OF A HIGHER DOSE OF OCRELIZUMAB IN ADULTS WITH PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS

The purpose of this study is to compare the effects, good or bad, of a higher dose of ocrelizumab versus the approved dose of ocrelizumab on participants with PPMS. In this study, you will get either the approved dose or a higher dose of ocrelizumab. 

multiple sclerosis
ocrelizumab
  • 0 views
  • 17 May, 2021
  • 1 location
featured
Multiple Sclerosis - (MS) Primary Progressive Multiple Sclerosis

Multiple Sclerosis - (MS) Primary Progressive Multiple Sclerosis

  • 334 views
  • 08 Nov, 2020
  • 1 location
featured
Exploring the safety and tolerability of conversion to dose-titrated Oral Siponimod in patients with advancing forms of relapsing multiple sclerosis: A 6-month open label, multi-center Phase IIIb study (EXCHANGE) Protocol Number: CBAF312AUS02

The purpose of the study is to see how safe it is and how well you tolerate changing the MS medicine you are taking currently for your MS to siponimod (an investigational drug for MS). The results

disease or disorder
glatiramer acetate
teriflunomide
fingolimod
dimethyl fumarate
  • 61 views
  • 24 Nov, 2020
  • 1 location
featured
Living with Multiple Sclerosis? Enrolling for a 96-week, non-placebo, comparative trial.

Living with Multiple Sclerosis? Enrolling for a 96-week, non-placebo, comparative trial.

  • 358 views
  • 08 Nov, 2020
  • 1 location
featured
A Placebo-controlled Randomized Withdrawal Evaluation of the Efficacy and Safety of Baclofen ER Capsules (GRS) in Subjects With Spasticity Due to Multiple Sclerosis

A Placebo-controlled Randomized Withdrawal Evaluation of the Efficacy and Safety of Baclofen ER Capsules (GRS) in Subjects With Spasticity Due to Multiple Sclerosis

  • 134 views
  • 08 Nov, 2020
  • 1 location
featured
Multicenter, Randomized, Double-blind, Parallel-group, Active-controlled, Superiority Study to Compare the Efficacy and Safety of Ponesimod to Teriflunomide in Subjects With Relapsing Multiple Sclerosis (OPTIMUM)

Multicenter, Randomized, Double-blind, Parallel-group, Active-controlled, Superiority Study to Compare the Efficacy and Safety of Ponesimod to Teriflunomide in Subjects With Relapsing Multiple

  • 284 views
  • 08 Nov, 2020
  • 1 location
Study to Evaluate the Efficacy and Safety of Dimethyl Fumarate (Tecfidera) and Peginterferon Beta-1a (Plegridy) for the Treatment of Relapsing-Remitting Multiple Sclerosis in Pediatric Participants

The main objective of the study is to evaluate the efficacy of dimethyl fumarate (Tecfidera) and peginterferon beta-1a (Plegridy), both compared with placebo, in pediatric participants with RRMS. The other objectives of this study are to evaluate the safety and tolerability of dimethyl fumarate and peginterferon beta-1a and to assess …

demyelination
relapsing multiple sclerosis
tecfidera
fumarate
  • 6 views
  • 01 Apr, 2021
  • 26 locations
A Study to Evaluate the Safety Tolerability and Efficacy of BIIB017 (Peginterferon Beta-1a) in Pediatric Participants for the Treatment of Relapsing-Remitting Multiple Sclerosis

This study will evaluate the safety, tolerability, and descriptive efficacy of BIIB017 in pediatric participants with relapsing-remitting multiple sclerosis (RRMS) and to assess the

magnetic resonance imaging brain
relapsing multiple sclerosis
interferon
  • 109 views
  • 27 Jul, 2021
  • 72 locations
Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168)

with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance and

hmr1726
aubagio
pregnancy test urine
contraceptive use
teriflunomide
  • 10 views
  • 28 Jun, 2021
  • 122 locations