Aggressive Fibromatosis Clinical Trials

A listing of Aggressive Fibromatosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 6 clinical trials
A Safety, Pharmacokinetic and Efficacy Study of a y-Secretase Inhibitor, Nirogacestat (PF-03084014) in Children and Adolescents With Progressive, Surgically Unresectable Desmoid Tumors

This phase II trial studies the side effects and how well nirogacestat works in treating patients patients less than 18 years of age with desmoid tumors that has grown after at least one form of

platelet count
metastatic disease
nonsteroidal anti-inflammatory drugs
stroke
cardiac dysrhythmias
  • 4 views
  • 13 Oct, 2022
  • 51 locations
A Randomized, Double-blind, Phase Ⅲ Study of Liposomal Doxorubicin in Desmoid Tumor

The aim of this study was to evaluate the efficacy and safety of liposomal doxorubicin in the treatment of desmoid tumors. Unless the subject withdraws from the trial voluntarily, or the

platelet count
nonsteroidal anti-inflammatory drugs
metastatic disease
renal function
hormone therapy
  • 0 views
  • 21 Oct, 2022
  • 1 location
The TNT Protocol: A Phase 2 Study Using Talimogene Laherparepvec,Nivolumab and Trabectedin as First, Second/Third Line Therapy for Advanced Sarcoma, Including Desmoid Tumor and Chordoma (TNT)

This is a Phase 2 study using talimogene laherparepvec, nivolumab, and trabectedin as first, second or third line therapy for advanced sarcoma, including desmoid tumor and chordoma.

platelet count
trabectedin
advanced sarcoma
kidney function tests
measurable disease
  • 37 views
  • 22 Oct, 2022
  • 1 location
The Project: EveryChild Protocol: A Registry, Eligibility Screening, Biology and Outcome Study

This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care.

langerhans cell histiocytosis
metastatic disease
carcinoma
nephroblastoma
desmoid tumors
  • 366 views
  • 13 Oct, 2022
  • 128 locations
Natural History and Biospecimen Acquisition Study for Children and Adults With Rare Solid Tumors

chordoma Desmoid Desmoplastic small round cell tumor Epithelioid hemangioendothelioma Esthenioneuroblastoma Ewing Sarcoma Fibrolamellar carcinoma

cns tumor
Accepts healthy volunteers
cancer
solid tumor
  • 36 views
  • 21 Oct, 2022
  • 4 locations
Observing People With Desmoid-Type Fibromatosis

The purpose of this study is to closely observe people with desmoid-type fibromatosis over 1 months.

MRI
fibromatosis
ct scan
  • 14 views
  • 07 Oct, 2022
  • 1 location