Aggressive Fibromatosis Clinical Trials

A listing of Aggressive Fibromatosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 13 clinical trials
Study of CB-103 in Adult Patients With Advanced or Metastatic Solid Tumours and Haematological Malignancies

This is a phase I/II, non randomized, open-label, dose escalation study to investigate the safety, tolerability and preliminary efficacy of CB-103.

solid tumour
blood transfusion
hormone therapy
metastasis
growth factor
  • 281 views
  • 26 Jan, 2021
  • 12 locations
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

>Desmoid tumors Peripheral nerve sheath tumors and NF1-related tumors (closed to accrual 09/19/2018) Malignant giant cell tumors Chordoma (closed to accrual 11/29/2018)

cancer other
carcinosarcoma
adenosarcoma
free thyroxine
thyroiditis
  • 5957 views
  • 19 Jun, 2021
  • 814 locations
A Study of AL102 in Patients With Progressing Desmoid Tumors

The current study is designed to evaluate the efficacy and safety of AL102 in patients with progressive desmoid tumors.

measurable disease
line of therapy
MRI
  • 0 views
  • 30 May, 2021
  • 1 location
Doxorubicin Eluting Intra-arterial Embolization for Aggressive Desmoid Fibromatosis

In this study Drug-eluting microbeads (DEB) loaded with Doxorubicin will be delivered into the target Desmoid Fibromatoses (DF) tissue via selective arterial embolization by angiographic

measurable disease
fibromatosis
nonsteroidal anti-inflammatory drugs
myelosuppressive chemotherapy
vinblastine
  • 17 views
  • 23 Jan, 2021
  • 1 location
A Study of a New Drug Nirogacestat for Treating Desmoid Tumors That Cannot be Removed by Surgery

This phase II trial studies the side effects and how well nirogacestat works in treating patients with desmoid tumors that has grown after at least one form of treatment by mouth or in the vein

stroke
stem cell transplantation
growth factor
temsirolimus
cardiac dysrhythmias
  • 0 views
  • 30 May, 2021
  • 39 locations
A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumor

This is a phase I/II, open-label, non-randomized, multicentre study to evaluate the clinical activity of vactosertib plus imatinib in desmoid tumor. Based on the background, TGFinhibition as a

measurable disease
fibromatosis
imatinib
vactosertib
ejection fraction
  • 44 views
  • 01 May, 2021
  • 1 location
Talimogene Laherparepvec Nivolumab and Trabectedin for Sarcoma

This is a Phase 2 study using talimogene laherparepvec, nivolumab, and trabectedin as first, second or third line therapy for advanced sarcoma, including desmoid tumor and chordoma.

measurable disease
kidney function tests
platelet count
metastatic sarcoma
trabectedin
  • 1 views
  • 24 Jan, 2021
  • 1 location
Safety and Efficacy Study Using 5-ALA Oral Administration as an Adjuvant Therapy on the Rate of Local Tumor Recurrence in Patients Who Have Desmoids Tumors

therapy on the 3 years rate of local tumor recurrence in patients with desmoid tumors. To evaluate the Safety of 5-ALA administration. 5 years local recurrence rate.

  • 39 views
  • 08 Nov, 2020
  • 1 location
Nivolumab (Opdivo ) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers

sarcoma, PEComa, epithelioid sarcoma, desmoid tumor, chordoma, non-small cell lung cancer, small cell lung cancer, urethelial carcinoma, melanoma, renal cell carcinoma, squamous cell carcinoma of head and

metastasis
squamous cell carcinoma of head and neck
lymphoma
nivolumab
chemotherapy regimen
  • 81 views
  • 15 May, 2021
  • 1 location
Project: Every Child for Younger Patients With Cancer

This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care.

carcinoma
bone marrow procedure
metastatic disease
nephroblastoma
desmoid tumors
  • 366 views
  • 31 May, 2021
  • 124 locations