Mood Disorders Clinical Trials

A listing of Mood Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 170 clinical trials
An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression

The purpose of this study is to evaluate the effectiveness of two adaptive treatment strategies (ATSs) for adolescent depression. The ATSs include delivery of an evidence-based psychotherapy (interpersonal psychotherapy for depressed adolescents, IPT-A), systematic symptom monitoring, and an empirically-derived algorithm that specifies whether, when, and how to augment IPT-A. Two …

depression
depressed mood
depressive symptoms
major depressive disorder
psychotherapy
  • 109 views
  • 06 May, 2022
  • 1 location
Cerebral Neuroinflammation During Major Depressive Episode (InflaDep)

the investigators make the following assumptions: 1) neuroinflammation in MDD can be measured by the [18 F ] DPA- 714 ; 2) it is accompanied by anatomical and functional changes in the frontal subcortical loops, strongly involved in MDD ; 3) neuroinflammation in patients might be a biomarker related to …

remission
blood tests
antidepressants
depressive episode
Accepts healthy volunteers
  • 7 views
  • 11 Apr, 2023
  • 3 locations
Mechanisms of Rumination Change in Adolescent Depression (RuMeChange)

This study will evaluate whether a newer treatment, rumination-focused cognitive behavioral treatment, which includes mindfulness and can be used to reduce ruminative habits, change ways in which key brain regions interact with each other (e.g.., often called connectivity), and whether these changes in habits and brain connectivity can reduce the …

remission
depression
depressed mood
major depressive disorder
behavior modification
  • 13 views
  • 20 Jun, 2022
  • 1 location
Efficacy of Light Therapy Device LUMINETTE® in Major Depressive Disorder (LUMIDEP)

This study evaluates the addition of light therapy with LUMINETTE device to usual treatment (antidepressant drug and psychotherapy) in the treatment of Major Depressive Disorder (MDD). Half of the participants will receive active light therapy with LUMINETTE device while the other half will receive placebo light therapy with LUMINETTE placebo …

major depressive disorder
antidepressants
depressive disorder
psychotherapy
  • 13 views
  • 04 Oct, 2022
  • 1 location
Clinical Effectiveness of Training for Awareness Resilience and Action (TARA) Compared to Standard Treatment for Adolescents and Young Adults With Depression, a Pragmatic Multi-center Randomised Controlled Superiority-trial (TARA)

Depressive Disorders constitute an increasing global health concern and available treatments for young people have not been sufficiently effective in haltering this trend. The novel group treatment program "Training for Awareness, Resilience, and Action" (TARA) was developed to target specific mechanisms based on neuroscientific findings in adolescent depression. TARA is …

anxiety
depressed mood
depressive disorder
depression
  • 0 views
  • 21 Oct, 2022
  • 2 locations
Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily Rhythms and Improve Brain Circuitry Functioning

The purpose of this study is to advance a non-pharmacologic suicide preventive intervention with wide dissemination potential as an innovative high-yield solution to reduce suicide rates. The investigators aim to achieve this with this study of Brain Emotion Circuitry Self-Monitoring and Regulation Therapy for Daily Rhythms (BE-SMART-DR), a modification of …

suicide
bipolar disorder
depressive disorder
  • 0 views
  • 04 Oct, 2022
  • 2 locations
Efficacy of the Mobile Application for Prediction and Prevention of Mood Episode Recurrence Based on Machine Learning

This study was designed to evaluate the efficacy of the mobile application named Circadian Rhythm for Mood (CRM), which was developed to prevent recurring episodes of mood disorders (major

depressive disorder
  • 0 views
  • 04 Oct, 2022
  • 1 location
Vortioxetine in the Treatment of Depression Associated With Head and Neck Cancers Undergoing Radiotherapy

The purpose of this study is to evaluate the effects of vortioxetine, once daily (QD), on mood disorders and cognitive dysfunction in patients with head and neck cancers undergoing radiotherapy

  • 0 views
  • 03 Apr, 2021
  • 1 location
Effects of an ER Beta Agonist (Lilly Compound LY500307) on Estradiol-Withdrawal-Induced Mood Symptoms in Women With Past Perimenopausal Depression

Background Some women who had depression in the perimenopause may have mood symptoms again if they stop estrogen therapy. Estrogen acts in the brain and other tissues by binding to at least three types of estrogen receptors. One of these receptors, estrogen receptor beta may affect anxiety and depression. The …

probe
blood tests
depression
estrogen
anxiety
  • 236 views
  • 06 Apr, 2023
  • 1 location
XEN1101 for Major Depressive Disorder

This project is designed to examine the neuronal KCNQ2/3 potassium (K+) channel subtype as a novel treatment target for mood disorders through the administration of the KCNQ-selective channel

  • 0 views
  • 11 Nov, 2021
  • 2 locations