Telomeres Clinical Trials

A listing of Telomeres medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 31 clinical trials
Featured trial
Low-Dose Danazol for the Treatment of Telomere Related Diseases

DNA is a structure in the body. It contains data about how the body develops and works. Telomeres are found on the end of chromosomes in DNA. Some people with short telomeres or other gene changes

pulmonary fibrosis
liver disease
hepatic fibrosis
lung disease
  • 22 Dec, 2020
  • 1 location
THIO Sequenced With Cemiplimab in Advanced NSCLC

preferentially incorporated into telomeres sequence in telomerase-positive cells leading to rapid telomere uncapping, genomic instability, and cell death. Cemiplimab is a programmed cell death protein 1

platelet count
kidney function test
cancer chemotherapy
platinum-based chemotherapy
neutrophil count
  • 04 Oct, 2022
  • 1 location
Low Dose Danazol for the Treatment of Telomere Related Diseases

Background DNA is a structure in the body. It contains data about how the body develops and works. Telomeres are found on the end of chromosomes in DNA. Some

  • 19 Oct, 2022
  • 1 location
Reducing African Americans' Alzheimer's Disease Risk Through Exercise (RAATE)" (RAATE)

, volume of whole brain and white matter hyperintensities, cardiorespiratory fitness, objectively measured physical activity, circulating hormones, and telomere length.

mental state examination
mini-mental state examination
Accepts healthy volunteers
  • 11 Mar, 2022
  • 1 location
Effects of Low Dose Aspirin in Bipolar Disorder (The A-Bipolar RCT)

Despite currently available treatment, a large proportion of patients with bipolar disorder (BD) suffer from affective symptoms, impaired psychosocial and cognitive function. Inflammation seems to be involved in the pathogenesis of BD and preliminary data suggest that low-dose Aspirin may have beneficial effects. The objective of this RCT is to …

  • 24 Apr, 2022
  • 1 location
A Randomized Controlled Trial Study To Evaluated the Effect of Exogenous Nucleotides as an Anti-ageing Supplement in Older Adults (60-70 Years)

To investigate the effects of dietary nucleotides (NTs) as an anti-aging supplement, a clinical trial is carried as a randomized, double-blind, parallel design, placebo-controlled. A total of 120 subjects will be enrolled in the study, and they shall be randomly distributed between the two arms, NTs-treated, and placebo-control. They would …

Accepts healthy volunteers
  • 21 Oct, 2022
DTG/3TC vs. BIC/FTC/TAF Maintenance Therapy in People Living With HIV: (PASO-DOBLE)

The hypothesize that DTG/3TC will be non-inferior to BIC/FTC/TAF with a 4% margin in virologically suppressed HIV-infected patients. The study will allow claiming for Superiority. Assuming that both DTG and BIC may lead to similar weight gains (approximately 1 kg after 48 weeks) in virologically suppressed HIV-infected patients and that …

  • 14 Jul, 2022
  • 20 locations
The TELO-SCOPE Study: Attenuating Telomere Attrition With Danazol. Is There Scope to Dramatically Improve Health Outcomes for Adults and Children With Pulmonary Fibrosis

care in pulmonary fibrosis associated with short telomeres is safe and will result in reduced telomere attrition.

pulmonary fibrosis
  • 30 Sep, 2021
  • 9 locations
Study to Evaluate of EXG34217 in Patients With Telomere Biology Disorders With Bone Marrow Failure

This is a Phase I/II, open label, single center study to assess the safety and tolerability of EXG34217 in bone marrow failure patients with telomere biology disorders.

  • 12 May, 2022
  • 1 location
Influence of Socioeconomic and Environmental Factors on the Natural History of Idiopathic Pulmonary Fibrosis

susceptibility (shorter telomeres) and that this effect is related to oxidative stress and shortening of telomeres.

pulmonary fibrosis
idiopathic pulmonary fibrosis
interstitial lung disease
diagnostic procedures
  • 02 Nov, 2021
  • 15 locations