Brain Function Clinical Trials

This is a research study that uses magnetic resonance imaging (MRI) to compare the brain structure, function and chemistry of typical adolescents tot hose with depression and/or anxiety.

The goal of this study is to learn more about Magnetic Resonance Imaging (MRI) and cognitive function over a 12 month period in people who have switched DMTs. In addition to your regular clinical care, you will be asked to answer questions about your health and complete the Single Digit ...

To evaluate patterns of brain function common among patients with dystonia in order to inform future treatment of the disease.  

Researchers at the University of Kentucky are inviting you to participate in a brain imaging study. The purpose of this study is to identify changes in cognitive and brain functions associated with aging. Financial compensation for participation is provided.  

This study is designed to test the hypothesis that poor cerebral perfusion during critical illness is a risk factor for acute and long-term neurological dysfunction among survivors. We use near-infrared spectroscopy to measure brain tissue oxygenation as a non-invasive surrogate marker for cerebral perfusion. Acute neurological dysfunction is defined as ...

Physical activity interventions conducted in supervised settings (laboratories and group settings) with older adults have consistently shown improved cardiovascular and cerebrovascular health and improved cognitive function. What is lacking is the development of interventions that take place in real world environments and that take advantage of new technologies to help ...

Arm and hand dysfunction, although not widely recognized, is a common and devastating consequence of traumatic brain injury (TBI). Recommendations have been published that encourage clinicians to include upper extremity retraining within the TBI population; however, very little research exists that will help inform treatments for this population. There is ...

The premise of this proposal is that the clinical efficacy of lithium in bipolar disorder, and its complex effects on multiple brain physiological functions, may be best deciphered using a network properties-metric approach. This approach is critical because it provides insight into the function of brain networks (e.g., resilience to ...

This proposed study aims to compare the effects of unilateral and bilateral transcutaneous electrical nerve stimulation (TENS). It will compare the effectiveness of bilateral TENS + task-oriented training (TOT) with unilateral TENS+TOTin improving upper limb function in patients with chronic stroke. The null hypothesis will be that bilateral TENS+TOT and ...

This project is a cross-sectional, observational mono-center study with prospective data collecting. This study aims to further explore quality of upper limb movement in relation to characteristics of visuospatial exploration in stroke subjects and healthy subjects by a applying comprehensive measurements of clinical scales and kinematic data in capacity- and ...