Dry Mouth Clinical Trials

A listing of Dry Mouth medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 19 clinical trials
A Randomized, Placebo-controlled, Double-blind, Multicenter Study to Assess the Efficacy and Safety of Nipocalimab in Adults With Primary Sjogren's Syndrome (pSS)

The purpose of this study is to evaluate the efficacy and safety of nipocalimab in participants with primary Sjogren's syndrome (pSS) versus placebo.

rheumatism
  • 61 views
  • 14 Oct, 2022
  • 60 locations
Blinded Dry Mouth Spray Crossover Study

To identify the effectiveness of two mouth sprays at relieving symptoms of xerostomia in patients who have received radiation for carcinoma of the head and neck. To assess patient quality

carcinoma
  • 2 views
  • 04 Oct, 2022
  • 2 locations
The Management of Radiotherapy-induced Hyposalivation Using Low-level Laser Therapy: A Case Series. (REACH-LLLT)

The primary purpose is to evaluate the effectiveness of photobiomodulation laser application in the management of patients with radiotherapy-induced hyposalivation. Secondary, to assess the

  • 0 views
  • 18 Oct, 2022
  • 1 location
Photobiomodulation on the Salivary Glands of Patients With Xerostomia Induced by the Use of Benzodiazepines

the oral cavity. Reductions in salivary flow are most often manifested as dry mouth, and this is the subjective complaint called xerostomia. Although xerostomia is the most frequent indication of

  • 0 views
  • 04 Oct, 2022
  • 1 location
Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sj(SqrRoot)(Delta)Gren's Syndrome; a Phase Ib-IIa Placebo-controlled Clinical Trial and Associated Mechanistic Studies

Background An autoimmune disease is one in which the immune system attacks a person s own body. Sjogren's syndrome (SS) is an autoimmune disease. It often involves multiple systems and organs of the body. Researchers are trying to find new, more effective and safe treatments for SS. Objective To evaluate …

autoimmune disease
hydroxychloroquine
glucocorticoids
tofacitinib
chloroquine
  • 0 views
  • 22 Oct, 2022
  • 1 location
ANIfrolumab Treatment for 24 Weeks in Patients With Primary Sjögren's Syndrome - Efficacy and Safety Assessment in a Randomized, Double-blind, Placebo-controlled Phase-IIa Proof-of-concept Trial (ANISE-II) (ANISE-II)

The ANISE-II study is a randomized, double-blind, placebo-controlled phase IIa proof-of-concept trial. Thirty patients with primary Sjögren's syndrome (pSS) are randomized in a 2:1 ratio to either anifrolumab or placebo treatment for 24 weeks. Main inclusion criteria are fulfilment of the ACR/EULAR classification criteria for pSS, disease duration of ≤10 …

  • 0 views
  • 17 Oct, 2022
  • 1 location
A Multi-center, Prospective, Open-label, Randomized Study to Explore Efficacy and Safety of Baricitinib in Active Primary Sjogren's Syndrome Patients

The investigators had observed that baricitinib was effective and safe in active pSS patients in a pilot study. So the investigators plan to conduct a multi-center, prospective, open-label, randomized study to compare the efficacy of baricitinib + hydroxychloroquine (HCQ) with HCQ alone in active pSS patients. The participants will be …

baricitinib
hydroxychloroquine
  • 0 views
  • 23 Oct, 2022
  • 1 location
CEQUA for Sjogren's Syndrome Dry Eye

The primary objective of this study is to show that CEQUA (cyclosporine 0.09% ophthalmic solution) improves symptoms of dry eye disease in a population of patients with Sjogren's Syndrome diagnosis.

  • 3 views
  • 04 Oct, 2022
  • 1 location
Phentermine/Topiramate in Adolescents With Type 2 Diabetes and Obesity

The most common side effects in these trials were paresthesia, dizziness, dysgeusia, insomnia, constipation, and dry mouth. Improvements were noted in blood pressure, lipids, glucose, insulin, HOMA-IR

insulin
topiramate
body mass index
diabetes
  • 0 views
  • 13 Oct, 2022
  • 1 location
Stereotactic Body Radiation Therapy or Intensity Modulated Radiation/Proton Therapy in Treating Patients With Recurrent Head and Neck Cancer

This phase II trial studies how well stereotactic body radiation therapy or intensity modulated radiation/proton therapy works in treating patients with head and neck cancer that has come back. Stereotactic body radiation therapy uses special equipment to position a patient and deliver radiation to tumors with high precision. This method …

intensity-modulated radiation therapy
tumor cells
x-rays
  • 3 views
  • 04 Oct, 2022
  • 1 location