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Dry Mouth Clinical Trials

A listing of Dry Mouth medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (12) clinical trials

"Hyaluronan" Formulation for Dry Mouth in Sleep Apnea Patients

During routine clinical practice, it is observed that patients with suspected obstructive sleep apnea (OSA) often reported waking up with a dry mouth during the night or in the morning. This 9 week, cross-over group, randomized, single center, study will evaluate the efficacy of a proprietary formulation in comforting dry ...

Phase N/A

Validation of the French Version of the Xerostomia Inventory

Medical context: There is an intra-individual and inter-individual variability in the production of saliva. Various factors influence the production of saliva. Saliva flow tends to decrease with age, sleep, emotional state, and to increase after eating, and during pregnancy. Some drugs increase the salivary flow, others decrease it. Tobacco and ...

Phase N/A

Early Phase Study Comparing the Effectiveness of a Dairy Product With the Reference Treatment Aequasyal on Dry Mouth Symptoms in Patients Suffering From Xerostomia Caused by Psychotropic Medications.

Dry mouth symptoms mostly occur as drug side-effects. Available products such as saliva substitutes are disappointing (bad taste, poor efficiency). The hypothesis stems from the "empirical" observations that many patients alleviate dry mouth symptoms by the consumption of dairy products. Through its composition, the dairy product in itself provides relief ...

Phase N/A

Effect of Pilocarpine in Patients With Xerostomia

There will be two groups: Group 1 (G1) - will use a spray with pilocarpine for three months and after a washout period of a month, use a spray without pilocarpine for another three months; Group 2 (G2) - will use a spray without pilocarpine for three months and after ...


Hypnosis for Treating Xerostomia Following Radiotherapy in Head & Neck Cancer Patients

10 head and neck cancer patients with xerostomia following radiotherapy will be assessed for severity of xerostomia using questionnares and quantitative salivation tests. patients responsive to citric acid will receive a hypnotic session with specific suggestion for salivation. saliva volume will be assessed pre and post hypnosis. patients will receive ...


Allogeneic Mesenchymal Stem Cells for Radiation-induced Hyposalivation and Xerostomia/Dry Mouth

Hyposalivation and xerostomia are the most common long-term side effects to radiotherapy of head and neck cancers. A randomized clinical trial indicates that autologeous mesenchymal stem/stromal cells can restore function of the submandibular glands. Patients with previous oropharynx cancer and radiation-induced hyposalivation and xerostomia will be treated with culture expanded ...


Photobiomodulation in Salivary Production of Patients With Xerostomy

Xerostomia is a quantitative and qualitative alteration of saliva, a symptom present in individuals who make continuous use of medications to control chronic diseases, including hypertension. Difficulties in mastication, swallowing, phonation and palate are present, besides oral burning syndrome, periodontal disease, root caries and bad breath that will interfere in ...


Everolimus in Restoring Salivary Gland Function in Participants With Locally Advanced Head and Neck Cancer Treated With Radiation Therapy

PRIMARY OBJECTIVES: I. To describe the recovery of salivary gland function after administration of a 5-day course of everolimus, administered two weeks after completion of radiation or chemoradiation therapy. SECONDARY OBJECTIVES: I. To describe the decrease of saliva flow rates during radiation or chemoradiation therapy. II. To describe the changes ...

Phase N/A

Effectiveness of Three Different Oral Moisturizers in Palliative Care Patients.

Background A majority of patients in palliative care have problems with dry mouth caused by medication or as a direct result of the mortal condition. Dry mouth will cause a variety of problems that commonly affect the disease negatively and contribute to reduced quality of life in the patient's last ...

Phase N/A

Effects of Aqualief in Patients With Xerostomia as Consequence of Radiotherapy for Head and Neck Cancer

Xerostomia is the biggest and chronic side effect of the RT for head and neck cancer. To treat xerostomia different approach should be followed at the same time: to increase existing saliva flow or replace lost secretions, to control the state of oral health, to control dental caries and to ...

Phase N/A