Alpha-1 Study: A research study for individuals with Alpha-1 Antitrypsin Deficiency

Last updated: N/A
Sponsor: N/A
Overall Status: Active - Recruiting

Phase

2

Condition

Alpha 1 Antitrypsin Deficiency

Treatment

N/A

Clinical Study ID

TX232161
  • Ages 18-78
  • All Genders

Study Summary

The Alpha-1 Study is a clinical research study currently enrolling individuals 18 to 78 (inclusive) with Alpha-1 Antitrypsin Deficiency.

The purpose of this study is to evaluate the safety, tolerability, and effectiveness of an investigational medication in individuals with Alpha-1 Antitrypsin Deficiency.

Interested individuals will be evaluated during a screening period to determine their eligibility to participate. Your participation could last approximately 11-16 weeks depending on whether or not you have ever been on augmentation therapy.

Those who qualify will receive all study-related medications and procedures at no cost.

You and your study doctor may choose to have some of the study visits at your home with a home health nurse, allowing for a reduced number of times that you must travel to the study site.

You may also be compensated financially for your study-related time and travel.

Eligibility Criteria

Inclusion

Inclusion Criteria:

  • Male or female between the ages of 18 and 78 (inclusive)
  • Female participants must be of non-childbearing potential (i.e., postmenopausal or have a history of hysterectomy or bilateral removal of the ovaries)
  • Diagnosed with Alpha-1 Antitrypsin Deficiency
  • Have the genetic pattern most commonly associated with Alpha-1 (the PiZZ genotype)
  • A genetic blood test will be used to confirm genotype
  • Have never been treated with gene therapy
  • Do not smoke cigarettes and/or use electronic nicotine delivery systems (i.e., electronic cigarettes, vape pens) or chewing tobacco products
  • Willing and able to comply with the study instructions
  • There are additional eligibility requirements, which the study doctor can explain to you

Study Design

Study Start date:
Estimated Completion Date:

Study Description

Visit [**Alpha1Trial.com**](https://alpha1trial.com/see-if-you-may- qualify?utm_source=centerwatch&utm_medium=listing&utm_campaign=pxmedia) to learn more.

Connect with a study center

  • Alpha 1 Study Center

    Gainesville, Florida 32610
    United States

    Active - Recruiting

  • Alpha 1 Study Center

    Orlando, Florida 32803
    United States

    Active - Recruiting

  • Alpha 1 Study Center

    Kansas City, Kansas 66160
    United States

    Active - Recruiting

  • Alpha 1 Study Center

    Hannibal, Missouri 63401
    United States

    Active - Recruiting

  • Alpha 1 Study Center

    Buffalo, New York 14202
    United States

    Active - Recruiting

  • Alpha 1 Study Center

    Chapel Hill, North Carolina 27517
    United States

    Active - Recruiting

  • Alpha 1 Study Center

    Houston, Texas 77380
    United States

    Active - Recruiting

  • Alpha 1 Study Center

    Salt Lake City, Utah 84108
    United States

    Active - Recruiting

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