DESCANSO, a Mental Health Intervention for Depression, Insomnia, and Fatigue Symptoms in Latino People With Cancer

Last updated: January 23, 2026
Sponsor: Memorial Sloan Kettering Cancer Center
Overall Status: Active - Recruiting

Phase

N/A

Condition

Neuroblastoma

Treatment

DESCANSO/Depresión/Depressed Mood, Cansancio/Fatigue, and Sueño/Sleep; Rest in English

Clinical Study ID

NCT07225088
25-277
  • Ages > 18
  • All Genders
  • Accepts Healthy Volunteers

Study Summary

The purpose of this study is to improve ways of providing mental health support to Spanish-speaking Latino participants who have cancer and experience depression, insomnia, and fatigue. Investigators will test a special mental health intervention called DESCANSO/REST (Depresión/Depressed Mood, Cansancio/Fatigue, and Sueño/Sleep). The intervention can be delivered through telehealth.

Eligibility Criteria

Inclusion

Provider Eligibility Criteria:

Participant eligibility will be determined by a self-report screener. Inclusion Criteria Self-Report Criteria

  • Mental health provider

  • Treats Latino cancer patients and/or survivors

  • Has at least 3 years of clinical experience providing psychosocial services to cancer patients and/or survivors

  • Able to read Spanish determined by the question: "Can you read in Spanish? Yes/No"

Patient Eligibility Criteria:

A patient cannot be considered eligible for this study unless ALL of the following conditions are met. Participant eligibility will be determined by an initial EMR review followed by a self-report screener.

Inclusion Criteria EMR Criteria

  • Documentation of Disease

o Pathologically confirmed solid tumor cancer (either most recent or new diagnosis)

  • Definition of Disease [or Measurable Disease]

o Diagnosed with stages I, II, or III

  • Prior Treatment

  • Currently undergoing systemic therapy (chemotherapy, radiation therapy, and/or immunotherapy) or within the first year following completion of systemic therapy Self-Report Criteria

  • Age ≥ 21 years

  • Lives in mainland U.S. or Puerto Rico

  • Identifies as Latino/a or Hispanic

  • Reports Spanish as their preferred language

  • Speaks Spanish "Very well" or "Well" as determined by the question: "How well do you speak Spanish?"

  • Presence of fatigue and disturbed sleep determined by a score of ≥ 3 on the MD Anderson Symptom Inventory

Exclusion Criteria EMR Criteria

o In the judgment of the treating physician, protocol investigators, and/or study staff, presence of cognitive impairment (e.g., delirium or dementia) sufficient to preclude meaningful informed consent and/or study participation

Self-Report Criteria

  • History of comorbidities within the last 12 months associated with fatigue and poor sleep, including hypothyroidism or abnormal thyroid function, sleep apnea, chronic obstructive pulmonary disease, neuromuscular disease, alcohol or drug abuse

  • Pregnant or lactating, women only

  • Presence of suicidal risk determined by any affirmative response on the Columbia-Suicide Severity Rating Scale

Study Design

Total Participants: 125
Treatment Group(s): 1
Primary Treatment: DESCANSO/Depresión/Depressed Mood, Cansancio/Fatigue, and Sueño/Sleep; Rest in English
Phase:
Study Start date:
January 23, 2026
Estimated Completion Date:
April 30, 2029

Connect with a study center

  • Memorial Sloan Kettering Cancer Center Basking Ridge (Limited Protocol Activities)

    Basking Ridge 5095409, New Jersey 5101760 07920
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

    Middletown 5101170, New Jersey 5101760 07748
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    Montvale 5101361, New Jersey 5101760 07645
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Suffolk-Commack (Limited protocol activity)

    Commack 5113412, New York 5128638 11725
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Westchester (Limited Protocol Activities)

    Harrison 5120095, New York 5128638 10604
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Cancer Center

    New York 5128581, New York 5128638 10065
    United States

    Active - Recruiting

  • Memorial Sloan Kettering Nassau (Limited Protocol Activites)

    Rockville Centre 5134203, New York 5128638 11553
    United States

    Active - Recruiting

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